Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.57 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 3/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2593641 | 0.85 | TAAR1 (0.70) | TAAR1PRKCQHTR2AHTR2CHTR2B | |
| SCHEMBL8227760 | 0.80 | TAAR1 (0.57) | TAAR1PRKCQHTR2AHTR2CHTR2B | |
| SCHEMBL22299378 | 0.79 | TAAR1 (0.61) | TAAR1PRKCQKIF11ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL3911403 | 0.78 | TAAR1 (0.55) | TAAR1HTR2AHTR2CHTR2BSLC6A4 | |
| SCHEMBL13385660 | 0.76 | HDAC8 (0.47) | TSHRKIF11CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL14991287 | 0.76 | TAAR1 (0.57) | TAAR1PRKCQHTR2AHTR2CHTR2B | |
| SCHEMBL3978037 | 0.76 | TAAR1 (0.57) | TAAR1PRKCQHTR2AHTR2CHTR2B | |
| SCHEMBL21277730 | 0.76 | TAAR1 (0.57) | TAAR1PRKCQHTR2AHTR2CHTR2B | |
| SCHEMBL2227553 | 0.76 | TAAR1 (0.57) | TAAR1PRKCQHTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL16007841 | 0.76 | TAAR1 (0.57) | TAAR1PRKCQHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011088181-A9 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2013-01-31 | — | — | WO | disclosed |
| WO-2011088181-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2011-07-21 | — | — | WO | disclosed |