SCHEMBL697802

SCHEMBL697802

Cc1cc(C(C)(C)c2cccc(C(C)(C)c3ccc(O)c(C)c3)c2)ccc1O

nearest known ligand 0.83

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 11/20 0.83
ESR2 Q92731 8/20 0.64
AR P10275 3/20 0.53
CNR1 P21554 3/20 0.50
CNR2 P34972 3/20 0.50
KLF10 Q13118 1/20 0.50
ALOX15 P16050 2/20 0.47
ALOX12 P18054 1/20 0.47
ALDH1A1 P00352 2/20 0.47
CYP3A4 P08684 1/20 0.47
TDP1 Q9NUW8 2/20 0.46
TP53 P04637 1/20 0.46
RORC P51449 1/20 0.46
HSD17B1 P14061 1/20 0.44
HSD17B2 P37059 1/20 0.44
HPGD P15428 1/20 0.43
HSD17B10 Q99714 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29696059 1.00 ESR1 (0.83) ESR1ESR2ARCNR1CNR2
SCHEMBL13059074 0.93 ESR1 (0.79) ESR1ESR2ARCNR1CNR2
SCHEMBL3913903 0.91 ESR1 (0.91) ESR1ESR2ARKLF10ALOX15
SCHEMBL35285 0.91 ESR1 (1.00) ESR1ESR2ARKLF10ALOX15
SCHEMBL29360146 0.91 ESR1 (1.00) ESR1ESR2ARKLF10ALOX15
SCHEMBL29350788 0.91 ESR1 (1.00) ESR1ESR2ARKLF10ALOX15
SCHEMBL24659659 0.90 ESR1 (0.74) ESR1ESR2ARCNR1CNR2
SCHEMBL7749004 0.90 ESR1 (0.74) ESR1ESR2ARCNR1CNR2
SCHEMBL2692670 0.90 ESR1 (0.80) ESR1ESR2ARCNR1CNR2
SCHEMBL29696084 0.89 ESR1 (0.95) ESR1ESR2ARCNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 335 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7109274-B2 Polyarylate compositions GENERAL ELECTRIC COMPANY (US) 2006-09-19 US claimed
EP-1543061-B1 METHOD OF PREPARING TRANSPARENT SILICONE-CONTAINING COPOLYCARBONATES GEN ELECTRIC (US) 2006-08-30 EP claimed
US-20060004152-A1 Polyarylate compositions GENERAL ELECTRIC COMPANY 2006-01-05 US claimed
EP-1543061-A1 METHOD OF PREPARING TRANSPARENT SILICONE-CONTAINING COPOLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2005-06-22 EP claimed
US-6833422-B2 Interfacial polymerization of polycarbonates with polysiloxanes, then endcapping to form haze-free polycarbonatepolysiloxane copolymers GENERAL ELECTRIC COMPANY 2004-12-21 US claimed
US-6780961-B2 CONVERTING OLIGOMERIC CHLOROFORMATES TO HIGH MOLECULAR WEIGHT POLYCARBONATE GENERAL ELECTRIC COMPANY 2004-08-24 US claimed
US-20040077820-A1 Method of making polycarbonate GENERAL ELECTRIC COMPANY 2004-04-22 US claimed
WO-2004016674-A1 METHOD OF PREPARING TRANSPARENT SILICONE-CONTAINING COPOLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2004-02-26 WO claimed
US-20040039145-A1 Method of preparing transparent silicone-containing copolycarbonates GENERAL ELECTRIC COMPANY 2004-02-26 US claimed
US-6657038-B1 Melt condensation copolymerization of dihydroxyaromatic compounds and diphenyl carbonate derivative in presence of metal hydroxide and quaternary phosphonium salt GENERAL ELECTRIC COMPANY 2003-12-02 US claimed
US-6248859-B1 CONTAINING SPIROBIINDANE UNITS; OPTICAL DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY 2001-06-19 US claimed
US-12509549-B2 Resin composition for laser direct structuring, molded article, and, method for manufacturing plated molded article MITSUBISHI CHEMICAL CORPORATION (JP) 2025-12-30 US disclosed
US-12139578-B2 Cover for millimeter-wave radar and millimeter-wave radar module including the same MITSUBISHI CHEMICAL CORPORATION (JP) 2024-11-12 US disclosed
US-11898025-B2 Polyethylene with additives for increased environmental stress crack resistance SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2024-02-13 US disclosed
US-11535732-B2 Polyethylene with polycarbonate-siloxane for increased environmental stress crack resistance SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2022-12-27 US disclosed
US-5665675-A THERMAL RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1997-09-09 US disclosed
EP-0570186-B1 Thermal recording sheet JUJO PAPER CO LTD (JP) 1997-08-13 EP disclosed
EP-0693386-B1 Aminobenzenesulfonamide derivatives as colour-developers for thermosensitive recording materials JUJO PAPER CO LTD (JP) 1997-02-05 EP disclosed
EP-0693386-A1 Aminobenzenesulfonamide derivatives as colour-developers for thermosensitive recording materials NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1996-01-24 EP disclosed
EP-0570186-A1 Thermal recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1993-11-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509549-B2 Resin composition for laser direct structuring, molded article, and, method for manufacturing plated molded article MECP2, POT1, EMG1 ESR1 2818/4885ESR2 2603/4885AR 3699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.