Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 12/20 | 0.62 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | PLG | P00747 | 1/20 | 0.55 |
| ▸ | PROC | P04070 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982485 | 1.00 | F10 (0.62) | F10PRSS1F2PLGPROC | |
| SCHEMBL6985029 | 0.91 | F10 (0.51) | F10PRSS1F2 | |
| SCHEMBL6978219 | 0.89 | F10 (0.55) | F10PRSS1F2 | |
| SCHEMBL6164332 | 0.86 | F10 (0.62) | F10PRSS1F2PLGPROC | |
| SCHEMBL6166353 | 0.86 | F10 (0.62) | F10PRSS1F2PLGPROC | |
| SCHEMBL6979556 | 0.85 | F10 (0.67) | F10PRSS1 | |
| SCHEMBL7494024 | 0.84 | F10 (0.60) | F10PRSS1F2PLGPROC | |
| SCHEMBL6163514 | 0.82 | F10 (0.54) | F10PRSS1F2PLGPROC | |
| SCHEMBL6979437 | 0.80 | F10 (0.73) | F10PRSS1 | |
| SCHEMBL6979424 | 0.80 | F10 (0.51) | F10PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934265-B1 | AMIDINOPHENYL-PYRROLIDINES, -PYRROLINES, AND -ISOXAZOLIDINES AND DERIVATIVES THEREOF | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2003-01-02 | — | — | EP | claimed |