Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 16/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70330 | 0.92 | SCD (0.49) | SCD | |
| SCHEMBL68809 | 0.92 | SCD (0.56) | SCD | |
| SCHEMBL29385115 | 0.92 | SCD (0.56) | SCD | |
| SCHEMBL70327 | 0.91 | SCD (0.46) | SCD | |
| SCHEMBL29384858 | 0.91 | SCD (0.46) | SCD | |
| SCHEMBL29385600 | 0.91 | SCD (0.50) | SCD | |
| SCHEMBL69244 | 0.91 | SCD (0.50) | SCD | |
| SCHEMBL29385059 | 0.90 | SCD (0.45) | SCD | |
| SCHEMBL69974 | 0.90 | SCD (0.45) | SCD | |
| SCHEMBL69827 | 0.89 | SCD (0.45) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129376-B2 | Piperidine derivatives as inhibitors of stearoyl-CoA desaturase | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2012-03-06 | — | — | US | disclosed |
| EP-2268143-A2 | NOVEL PIPERIDINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | Forest Laboratories Holdings Limited (BM) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009117676-A2 | NOVEL PIPERIDINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2009-09-24 | — | — | WO | disclosed |