Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | HPN | P05981 | 2/20 | 0.46 |
| ▸ | HGFAC | Q04756 | 2/20 | 0.46 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7081704 | 0.97 | F2 (0.45) | F2HPNHGFACST14F10 | |
| SCHEMBL5860352 | 0.95 | PRSS1 (0.46) | — | |
| SCHEMBL6972556 | 0.91 | — | — | |
| SCHEMBL18866677 | 0.88 | F2 (0.47) | F2 | |
| SCHEMBL18866505 | 0.88 | F2 (0.47) | F2 | |
| SCHEMBL5861617 | 0.85 | F2 (0.46) | F2 | |
| SCHEMBL18837911 | 0.84 | F2 (0.43) | F2 | |
| SCHEMBL18866601 | 0.84 | F2 (0.43) | F2 | |
| SCHEMBL18866492 | 0.84 | F2 (0.43) | F2 | |
| SCHEMBL18866597 | 0.84 | F2 (0.43) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833839-B1 | PEPTIDYL HETEROCYCLES USEFUL IN THE TREATMENT OF THROMBIN RELATED DISORDERS | ORTHO PHARMA CORP (US) | 2003-01-08 | — | — | EP | claimed |