Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9133433 | 0.79 | MAPT (0.42) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL1521680 | 0.74 | — | — | |
| SCHEMBL1236748 | 0.74 | — | — | |
| SCHEMBL6474317 | 0.74 | — | — | |
| SCHEMBL847381 | 0.73 | MAPT (0.48) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL847380 | 0.73 | MAPT (0.48) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL669112 | 0.72 | TSHR (0.55) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL1521429 | 0.72 | TSHR (0.55) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL21219349 | 0.72 | TSHR (0.55) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL21219314 | 0.72 | TSHR (0.55) | MAPTABCC4ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080089-B1 | PYRAZOLYLDIOXOTHIOCHROMANOYL DERIVATIVES | BASF AG (DE) | 2003-11-05 | — | — | EP | disclosed |