SCHEMBL6979878

SCHEMBL6979878

O=C(NCCN1CCOCC1)NC1CN(CC2CC2)CCC1CN1CCC[C@@H](Cc2ccc(F)cc2)C1

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CCR3 P51677 20/20 0.58
CYP2D6 P10635 7/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6354776 1.00 CCR3 (0.58) CCR3CYP2D6
SCHEMBL6354770 1.00 CCR3 (0.58) CCR3CYP2D6
SCHEMBL6983961 0.94 CCR3 (0.55) CCR3CYP2D6
SCHEMBL6355606 0.94 CCR3 (0.55) CCR3CYP2D6
SCHEMBL6355603 0.94 CCR3 (0.55) CCR3CYP2D6
SCHEMBL6344725 0.93 CCR3 (0.60) CCR3CYP2D6
SCHEMBL6344722 0.93 CCR3 (0.60) CCR3CYP2D6
SCHEMBL6347652 0.92 CCR3 (0.62) CCR3CYP2D6
SCHEMBL6347649 0.92 CCR3 (0.62) CCR3CYP2D6
SCHEMBL6348489 0.90 CCR3 (0.61) CCR3CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1296978-A2 N-UREIDOHETEROCYCLOAKLYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY BRISTOL-MYERS SQUIBB COMPANY (US) 2003-04-02 EP claimed
WO-2002002525-A2 N-UREIDOHETEROCYCLOAKLYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2002-01-10 WO claimed
EP-1296978-A2 N-UREIDOHETEROCYCLOAKLYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY BRISTOL-MYERS SQUIBB COMPANY (US) 2003-04-02 EP disclosed
WO-2002002525-A2 N-UREIDOHETEROCYCLOAKLYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2002-01-10 WO disclosed