SCHEMBL6980107

SCHEMBL6980107

CCCCCCCCOc1cnc(-c2ccc(O)cc2)nc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.65
LTA4H P09960 2/20 0.57
RAB9A P51151 7/20 0.56
NPC1 O15118 6/20 0.56
SMN1; SMN2 Q16637 4/20 0.56
KDM4E B2RXH2 4/20 0.56
HSD17B10 Q99714 2/20 0.56
RARB P10826 4/20 0.50
MAPT P10636 3/20 0.50
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
STAT3 P40763 1/20 0.48
ATM Q13315 1/20 0.48
ALDH1A1 P00352 3/20 0.47
HPGD P15428 2/20 0.47
USP2 O75604 1/20 0.47
GAA P10253 1/20 0.47
TP53 P04637 1/20 0.46
TSHR P16473 1/20 0.46
ALDH2 P05091 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6976554 1.00 NR5A1 (0.65) NR5A1LTA4HRAB9ANPC1SMN1; SMN2
SCHEMBL6534793 1.00 NR5A1 (0.65) NR5A1LTA4HRAB9ANPC1SMN1; SMN2
SCHEMBL10346198 1.00 NR5A1 (0.65) NR5A1LTA4HRAB9ANPC1SMN1; SMN2
SCHEMBL8387949 1.00 NR5A1 (0.65) NR5A1LTA4HRAB9ANPC1SMN1; SMN2
SCHEMBL7061013 1.00 NR5A1 (0.65) NR5A1LTA4HRAB9ANPC1SMN1; SMN2
SCHEMBL7865004 0.98 NR5A1 (0.63) NR5A1LTA4HRAB9ANPC1SMN1; SMN2
SCHEMBL8436081 0.98 NR5A1 (0.63) NR5A1LTA4HRAB9ANPC1SMN1; SMN2
SCHEMBL7089844 0.98 NR5A1 (0.62) NR5A1LTA4HRAB9ANPC1SMN1; SMN2
SCHEMBL9228047 0.90 NR5A1 (0.69) NR5A1LTA4HRAB9ANPC1SMN1; SMN2
SCHEMBL6255603 0.90 NR5A1 (0.69) NR5A1LTA4HRAB9ANPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0549279-B1 Optically active pyrimidine compound, process for producing the same and liquid crystal composition containing the same SUMITOMO CHEMICAL CO (JP) 2000-03-29 EP claimed
US-5326871-A Optically active pyrimidine compound, process for producing the same and liquid crystal composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-07-05 US claimed
EP-0549279-A1 Optically active pyrimidine compound, process for producing the same and liquid crystal composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-30 EP claimed
JP-9031028-A None JP disclosed
JP-63005084-A None JP disclosed
CN-100338175-C Chiral liquid crystal compounds having fluorine-containing terminal moieties MINNESOTA MINING & MFG (US) 2007-09-19 CN disclosed
CN-1162406-C Liquid crystal compounds having chiral fluorinated terminal portion 美国3M公司 2004-08-18 CN disclosed
EP-1042302-B1 LIQUID CRYSTAL COMPOUNDS HAVING A CHIRAL FLUORINATED TERMINAL PORTION MINNESOTA MINING & MFG (US) 2003-09-24 EP disclosed
EP-0868501-B1 PROCESS FOR CONTROLLING CONE TILT ANGLE IN MIXTURES OF SMECTIC LIQUID CRYSTAL COMPOUNDS MINNESOTA MINING & MFG (US) 2003-08-13 EP disclosed
EP-0821719-B1 LIQUID CRYSTAL COMPOUNDS HAVING A CHIRAL FLUORINATED TERMINAL PORTION MINNESOTA MINING & MFG (US) 2003-01-02 EP disclosed
CN-1326494-A Chiral liquid crystal compounds having fluorinated terminal portion MINNESOTA MINING & MFG (US) 2001-12-12 CN disclosed
EP-0469893-A1 Fluorinated pyrimidine-phenyl optically active compounds and liquid crystal compositions thereof Takasago International Corporation (JP) 1992-02-05 EP disclosed
EP-0467721-A1 Optically active compound having a delta- valerolactone ring and liquid crystal composition containing same MITSUBISHI RAYON CO., LTD (JP) 1992-01-22 EP disclosed
US-4980082-A DISPLAY ELEMENTS; HIGH SPEED RESPONSE TO ELECTRICAL FIELDS SEIKO INSTRUMENTS INC. (JP) 1990-12-25 US disclosed
EP-0360622-A2 Novel optically active benzene derivatives, process for producing the same and liquid-crystalline composition containing said derivatives as liquid-crystalline compound and light switching elements SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-03-28 EP disclosed
EP-0355008-A2 Organosilylalkyl or -alkenyl compounds, process for their preparation and their use in liquid-crystal mixtures HOECHST AKTIENGESELLSCHAFT (DE) 1990-02-21 EP disclosed
EP-0354355-A1 Optically active compound and liquid crystal composition MITSUBISHI RAYON CO., LTD. (JP) 1990-02-14 EP disclosed
EP-0262809-A1 Pyrimidinylphenyl ester compound TEIKOKU CHEMICAL INDUSTRY CO., LTD. (JP) 1988-04-06 EP disclosed
JP-S635084-A 2-PHENYLPYRIMIDINE DERIVATIVE TEIKOKU CHEM IND CORP LTD 1988-01-11 JP disclosed
EP-0225195-A1 Phenylpyrimidine-based compounds and liquid crystal composition containing the same AJINOMOTO CO., INC. (JP) 1987-06-10 EP disclosed