Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | UBE2N | P61088 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
| ▸ | ODC1 | P11926 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6980030 | 1.00 | HTR2C (0.41) | HTR2CHTR2BHTTNPSR1MEN1 | |
| SCHEMBL12748472 | 1.00 | HTR2C (0.41) | HTR2CHTR2BHTTNPSR1MEN1 | |
| SCHEMBL11098662 | 0.81 | HTR2C (0.44) | HTR2CHTR2BHTTNPSR1MEN1 | |
| SCHEMBL21257372 | 0.80 | PTGS1 (0.37) | MEN1MAPTKMT2ATSHRMAPK1 | |
| SCHEMBL6981088 | 0.78 | NPSR1 (0.43) | HTR2CNPSR1PTGS1PTGS2XDH | |
| SCHEMBL9208134 | 0.76 | HIF1A (0.43) | MAPTALDH1A1 | |
| SCHEMBL9206139 | 0.75 | CA12 (0.40) | KDM4EPTGS1PTGS2XDH | |
| SCHEMBL6980284 | 0.75 | CA12 (0.40) | KDM4EPTGS1PTGS2XDH | |
| SCHEMBL928563 | 0.74 | CA9 (0.44) | HTTMEN1MAPTKMT2ATSHR | |
| SCHEMBL9205782 | 0.74 | CA9 (0.44) | HTTMEN1MAPTKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228058-B1 | BENZOPYRANYL GUANIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DONGBU HANNONG CHEMICAL CO LTD (KR) | 2003-12-10 | — | — | EP | disclosed |