Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 4/20 | 0.43 |
| ▸ | EDNRA | P25101 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HBB | P68871 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10849582 | 0.76 | EDNRA (0.41) | EDNRBEDNRAMAPTCYP1A2MEN1 | |
| SCHEMBL10845694 | 0.75 | EDNRA (0.40) | EDNRBEDNRAMAPTCYP1A2MEN1 | |
| SCHEMBL68089 | 0.74 | MAPT (0.53) | MAPTHTTHBBALOX15SMN1; SMN2 | |
| SCHEMBL13535002 | 0.70 | HTT (0.37) | EDNRBEDNRAMAPTHTTHBB | |
| SCHEMBL10411385 | 0.69 | HTT (0.36) | EDNRBEDNRAMAPTHTTHBB | |
| SCHEMBL7015084 | 0.67 | MEN1 (0.42) | HTTALOX15SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL68097 | 0.67 | PIM1 (0.39) | MAPTHTTHBBALOX15SMN1; SMN2 | |
| SCHEMBL2171598 | 0.67 | MAPT (0.50) | EDNRBEDNRAMAPTHTTHBB | |
| SCHEMBL13940537 | 0.66 | MEN1 (0.41) | MAPTHTTALOX15SMN1; SMN2CYP1A2 | |
| SCHEMBL9462052 | 0.66 | KDM4E (0.60) | MAPTCYP1A2CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080089-B1 | PYRAZOLYLDIOXOTHIOCHROMANOYL DERIVATIVES | BASF AG (DE) | 2003-11-05 | — | — | EP | claimed |
| US-6326333-B1 | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2001-12-04 | — | — | US | claimed |
| US-6326333-B1 | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2001-12-04 | — | — | US | disclosed |