Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23914323 | 0.72 | CYP19A1 (0.39) | SMN1; SMN2HDAC4SLC18A3GAAALDH1A1 | |
| SCHEMBL23914097 | 0.72 | CYP19A1 (0.39) | SMN1; SMN2HDAC4SLC18A3GAAALDH1A1 | |
| SCHEMBL29215625 | 0.71 | SLC18A3 (0.57) | SMN1; SMN2SLC18A3ALDH1A1TSHR | |
| Biphenyl SCHEMBL10346569 | 0.71 | SLC18A3 (0.57) | SMN1; SMN2SLC18A3ALDH1A1TSHR | |
| SCHEMBL2810288 | 0.70 | SLC18A3 (0.61) | SMN1; SMN2SLC18A3ALDH1A1TSHR | |
| SCHEMBL1524763 | 0.70 | TSHR (0.50) | TSHRSLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL10347924 | 0.70 | SLC18A3 (0.55) | SMN1; SMN2SLC18A3ALDH1A1TSHR | |
| SCHEMBL779924 | 0.70 | SLC18A3 (0.55) | SMN1; SMN2SLC18A3ALDH1A1TSHR | |
| SCHEMBL11099008 | 0.70 | SLC18A3 (0.55) | SMN1; SMN2SLC18A3ALDH1A1TSHR | |
| SCHEMBL6909318 | 0.68 | TSHR (0.43) | SMN1; SMN2TSHRSLC6A2SLC6A3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724569-B1 | PROCESS FOR THE PREPARATION OF AN OXIRANE, AZIRIDINE OR CYCLOPROPANE | AVECIA LTD (GB) | 2003-03-12 | — | — | EP | disclosed |
| US-5703246-A | REACTING AN ORGANOMETALLIC COMPOUND WITH ORGANOSULFUR COMPOUND | ZENECA LIMITED (GB) | 1997-12-30 | — | — | US | disclosed |
| EP-0724569-A1 | PROCESS FOR THE PREPARATION OF AN OXIRANE, AZIRIDINE OR CYCLOPROPANE | ZENECA LIMITED (GB) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995011230-A1 | PROCESS FOR THE PREPARATION OF AN OXIRANE, AZIRIDINE OR CYCLOPROPANE | ZENECA LIMITED (GB) | 1995-04-27 | — | — | WO | disclosed |