SCHEMBL6980819

SCHEMBL6980819

C1=CNC=CN=1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL519011 0.61
SCHEMBL2024 0.53
SCHEMBL18781531 0.50
SCHEMBL17508967 0.48
SCHEMBL21516574 0.42
SCHEMBL194486 0.38
Potassium Ion SCHEMBL1220493 0.29
Potassium Ion SCHEMBL23462035 0.25 CA4 (0.50)
Potassium Ion SCHEMBL23462233 0.25 CA4 (0.50)
Potassium Ion SCHEMBL23462122 0.25 CA4 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117642404-A Small molecule modulators of glucocerebrosidase activity and uses thereof 凡况生化公司 2024-03-01 CN disclosed
US-11839679-B2 Gamma-diketones for treatment and prevention of aging skin and wrinkles BIOSPLICE THERAPEUTICS, INC. (US) 2023-12-12 US disclosed
US-11672172-B2 Heterocyclic compound comprising aromatic amine group and organic light-emitting diode including the same SFC CO., LTD. (KR) 2023-06-06 US disclosed
WO-2023096987-A1 BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE ARVINAS OPERATIONS, INC. (US) 2023-06-01 WO disclosed
CN-111278825-B Diazaspiro ROCK inhibitors 百时美施贵宝公司 2023-05-02 CN disclosed
US-20230002356-A1 COMPOUNDS AND USES THEREOF PANO THERAPEUTICS, INC. (US) 2023-01-05 US disclosed
US-20220395503-A1 PYRUVATE KINASE ACTIVATORS FOR USE IN TREATING BLOOD DISORDERS AGIOS PHARMACEUTICALS, INC. 2022-12-15 US disclosed
US-11351168-B1 2,4-disubstituted pyrimidines useful as kinase inhibitors CELGENE CAR LLC (BM) 2022-06-07 US disclosed
US-20220087917-A1 GAMMA-DIKETONES FOR TREATMENT AND PREVENTION OF AGING SKIN AND WRINKLES VICKERS VENTURE FUND VI PTE. LTD. (SG) 2022-03-24 US disclosed
US-11192891-B2 Diazaspiro ROCK inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2021-12-07 US disclosed
US-9695132-B2 Heteroaryl compounds and uses thereof CELGENE CAR LLC (BM) 2017-07-04 US disclosed
US-9676785-B2 HCV protease inhibitors and uses thereof CELGENE CAR LLC (BM) 2017-06-13 US disclosed
US-9663524-B2 Substituted pyrido[2,3-d]pyrimidines as protein kinase inhibitors CELGENE CAR LLC (BM) 2017-05-30 US disclosed
US-20170137406-A1 ERK INHIBITORS AND USES THEREOF BRISTOL-MYERS SQUIBB COMPANY 2017-05-18 US disclosed
US-20170119907-A1 Targeted Therapeutics MEDIVATION TECHNOLOGIES, INC. (US) 2017-05-04 US disclosed
US-20170062729-A1 HETEROCYCLIC COMPOUND COMPRISING AROMATIC AMINE GROUP AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SFC CO., LTD. (KR) 2017-03-02 US disclosed
WO-2017014191-A1 COMPOUND, RESIN, UNDERLAYER FILM FORMING MATERIAL FOR LITHOGRAPHY, COMPOSITION FOR FORMING UNDERLAYER FILM FOR LITHOGRAPHY, UNDERLAYER FILM FOR LITHOGRAPHY, RESIST PATTERN FORMING METHOD, CIRCUIT PATTERN FORMING METHOD, AND PURIFICATION METHOD 三菱瓦斯化学株式会社 2017-01-26 WO disclosed
EP-1159276-B1 BENZOFURAN-2-ONES AS COLORANTS FOR ORGANIC MATERIALS CIBA SC HOLDING AG (CH) 2003-10-22 EP disclosed
EP-1159276-A2 BENZOFURAN-2-ONES AS COLORANTS FOR ORGANIC MATERIALS Ciba SC Holding AG (CH) 2001-12-05 EP disclosed
WO-2000053597-A2 BENZOFURAN-2-ONES AS COLORANTS FOR ORGANIC MATERIALS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-09-14 WO disclosed