SCHEMBL6981333

SCHEMBL6981333

O=C(c1cccc(-c2ccccc2)c1)c1cn(Cc2c[nH]cn2)cc1-c1cccc2ccccc12

nearest known ligand 0.59

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FNTA P49354 16/20 0.59
FNTB P49356 16/20 0.59
CNR1 P21554 2/20 0.40
CNR2 P34972 2/20 0.40
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6978911 0.93 FNTA (0.59) FNTAFNTBCNR1CNR2MEN1
SCHEMBL6975762 0.92 FNTA (0.66) FNTAFNTBCNR2
SCHEMBL6976044 0.89 FNTA (0.56) FNTAFNTBCNR2HTTKMT2A
SCHEMBL6969780 0.89 FNTA (0.69) FNTAFNTBCNR2MEN1MAPT
SCHEMBL6980497 0.86 FNTA (0.52) FNTAFNTBCNR2
SCHEMBL6972829 0.86 FNTA (0.58) FNTAFNTBCNR2
SCHEMBL6984623 0.85 FNTA (0.56) FNTAFNTBCNR1CNR2MEN1
SCHEMBL6925142 0.85 FNTA (0.53) FNTAFNTBMEN1KMT2A
SCHEMBL6973852 0.85 FNTA (0.53) FNTAFNTBCNR2
SCHEMBL6972826 0.85 FNTA (0.68) FNTAFNTBCNR2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1045846-B1 IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF LG CHEMICAL LTD (KR) 2003-05-02 EP claimed
US-6268363-B1 ANTITUMOR LG CHEMICAL LTD. (KR) 2001-07-31 US claimed