Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.37 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.37 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL698180 | 1.00 | MAPT (0.45) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL648855 | 0.93 | MAPT (0.44) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL648856 | 0.93 | MAPT (0.44) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL651242 | 0.92 | MAPT (0.43) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL651243 | 0.92 | MAPT (0.43) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL653877 | 0.91 | MAPT (0.48) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL653878 | 0.91 | MAPT (0.48) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL650979 | 0.91 | MAPT (0.42) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL650980 | 0.91 | MAPT (0.42) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL649349 | 0.90 | MAPT (0.42) | MAPTLMNANPSR1RECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423204-A1 | THIAZOLIDINONE DERIVATIVE | SBI Biotech Co., Ltd. (JP) | 2012-02-29 | — | — | EP | disclosed |