Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 9/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5755499 | 0.93 | SLC2A1 (0.48) | SLC2A1KCNH2SIGMAR1 | |
| SCHEMBL5755501 | 0.93 | SLC2A1 (0.48) | SLC2A1KCNH2SIGMAR1 | |
| SCHEMBL5755495 | 0.93 | SLC2A1 (0.48) | SLC2A1KCNH2SIGMAR1 | |
| SCHEMBL5758524 | 0.91 | SLC2A1 (0.47) | SLC2A1KCNH2SIGMAR1 | |
| SCHEMBL5758527 | 0.91 | SLC2A1 (0.47) | SLC2A1KCNH2SIGMAR1 | |
| SCHEMBL5758157 | 0.87 | SLC2A1 (0.48) | SLC2A1KCNH2SIGMAR1 | |
| SCHEMBL5756002 | 0.87 | SLC2A1 (0.48) | SLC2A1KCNH2SIGMAR1 | |
| SCHEMBL5758163 | 0.87 | SLC2A1 (0.48) | SLC2A1KCNH2SIGMAR1 | |
| SCHEMBL5752225 | 0.86 | SLC2A1 (0.51) | SLC2A1KCNH2 | |
| SCHEMBL7086857 | 0.86 | SLC2A1 (0.51) | SLC2A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343765-A1 | QUINOLINES AND NITROGENATED DERIVATIVES THEREOF SUBSTITUTED IN 4-POSITION BY A PIPERAZINE-CONTAINING MOIETY AND THEIR USE AS ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 2003-09-17 | — | — | EP | claimed |
| WO-2002050040-A1 | QUINOLINES AND NITROGENATED DERIVATIVES THEREOF SUBSTITUTED IN 4-POSITION BY A PIPERAZINE-CONTAINING MOIETY AND THEIR USE AS ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 2002-06-27 | — | — | WO | claimed |