⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5421586 | 0.63 | — | — | |
| SCHEMBL7964249 | 0.57 | TSHR (0.50) | — | |
| SCHEMBL9246090 | 0.54 | — | — | |
| SCHEMBL7885852 | 0.54 | — | — | |
| SCHEMBL9564850 | 0.54 | — | — | |
| SCHEMBL446727 | 0.54 | — | — | |
| Hydrochloric Acid SCHEMBL8314010 | 0.48 | — | — | |
| SCHEMBL10982343 | 0.48 | — | — | |
| SCHEMBL1157926 | 0.42 | — | — | |
| SCHEMBL1292065 | 0.42 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1854135-A | Heteronuclear compound with dicyandiamide connection and its medicinal use | LI WEIZHANG (CN) | 2006-11-01 | — | — | CN | claimed |
| JP-2115159-A | — | — | None | — | — | JP | disclosed |
| JP-2101069-A | — | — | None | — | — | JP | disclosed |
| CN-1854135-B | Heteronuclear compound with dicyandiamide connection and its medicinal use | LI WEIZHANG | 2013-06-12 | — | — | CN | disclosed |
| CN-1854135-A | Heteronuclear compound with dicyandiamide connection and its medicinal use | LI WEIZHANG (CN) | 2006-11-01 | — | — | CN | disclosed |
| EP-0846111-B1 | SYNTHESES OF OPTICALLY PURE COMPOUNDS USEFUL AS GARFT INHIBITORS AND THEIR INTERMEDIATES | AGOURON PHARMA (US) | 2003-08-27 | — | — | EP | disclosed |
| EP-1109560-B1 | COMPOUNDS USEFUL AS AICARFT INHIBITORS | AGOURON PHARMA (US) | 2003-08-27 | — | — | EP | disclosed |
| US-20030138432-A1 | Selective cellular targeting: multifunctional delivery vehicles, multifunctional prodrugs, use as antineoplastic drugs | DRUG INNOVATION & DESIGN, INC. | 2003-07-24 | — | — | US | disclosed |
| US-20020173515-A1 | Antiproliferative substituted 5-thiapyrimidinone and 5-selenopyrimidinone compounds | VARNEY MICHAEL D (US) | 2002-11-21 | — | — | US | disclosed |
| EP-1255567-A1 | SELECTIVE CELLULAR TARGETING: MULTIFUNCTIONAL DELIVERY VEHICLES | Drug Innovation & Design, Inc. (US) | 2002-11-13 | — | — | EP | disclosed |
| CN-1026587-C | Process for preparing 1, 3, 5-thiadiazin-4-one derivatives | KOREA CHEMICAL INSTITUDE (KR) | 1994-11-16 | — | — | CN | disclosed |
| CN-1026587-C | Process for preparing 1, 3, 5-thiadiazin-4-one derivatives | KOREA CHEMICAL INSTITUDE (KR) | 1994-11-16 | — | — | CN | disclosed |
| WO-1994013295-A1 | ANTIPROLIFERATIVE SUBSTITUTED 5-THIAPYRIMIDINONE AND 5-SELENOPYRIMIDINONE COMPOUNDS | AGOURON PHARMACEUTICALS, INC. (US) | 1994-06-23 | — | — | WO | disclosed |
| US-5284844-A | 3,5-Dihalogeno-1,2,6-thiadiazin-4-ones | FMC CORPORATION (US) | 1994-02-08 | — | — | US | disclosed |
| US-5077423-A | Intermediates for 1,3,5-thiadiazine-4-one derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1991-12-31 | — | — | US | disclosed |
| US-5077423-A | Intermediates for 1,3,5-thiadiazine-4-one derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1991-12-31 | — | — | US | disclosed |
| JP-H02115159-A | S-(N-ALKOXYCARBONYL-N-SUBSTITUTED)AMINOMETHYL ISOTHIOUREA DERIVATIVE | KOREA RES INST CHEM TECHNOL | 1990-04-27 | — | — | JP | disclosed |
| JP-H02101069-A | 1,3,5-THIADIAZIN-4-ONE DERIVATIVE, PRODUCTION THEREOF AND INSECTICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT | SUMITOMO CHEM CO LTD | 1990-04-12 | — | — | JP | disclosed |
| EP-0358416-A1 | S-(N-alkoxycarbonyl, N-substituted) amino-methyl isothiourea derivative | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1990-03-14 | — | — | EP | disclosed |
| EP-0358416-A1 | S-(N-alkoxycarbonyl, N-substituted) amino-methyl isothiourea derivative | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1990-03-14 | — | — | EP | disclosed |