Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 15/20 | 0.69 |
| ▸ | FNTB | P49356 | 15/20 | 0.69 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6978951 | 0.93 | FNTA (0.69) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL6978815 | 0.93 | FNTA (0.67) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL6981647 | 0.93 | FNTA (0.69) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL6982437 | 0.93 | FNTA (0.69) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL6981839 | 0.93 | FNTA (0.69) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL6926512 | 0.90 | FNTA (0.72) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL6978128 | 0.90 | FNTA (0.67) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL6925962 | 0.89 | FNTA (0.70) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL6983323 | 0.87 | FNTA (0.76) | FNTAFNTBPGGT1BCYP3A4HTR2C | |
| SCHEMBL6983878 | 0.87 | FNTA (0.76) | FNTAFNTBPGGT1BCYP3A4HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045846-B1 | IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD (KR) | 2003-05-02 | — | — | EP | claimed |
| US-6472526-B1 | SHOWS AN INHIBITORY ACTIVITY AGAINST FARNESYL TRANSFERASE OR PHARMACEUTICALLY ACCEPTABLE SALTS OR ISOMERS THEREOF, IN PHARMACEUTICAL COMPOSITION AND INTERMEDIATES | LG CHEMICAL LTD. (KR) | 2002-10-29 | — | — | US | disclosed |