Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 15/20 | 0.63 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6328962 | 0.81 | HCRTR2 (0.67) | HCRTR2HCRTR1MAPTALDH1A1KDM4E | |
| SCHEMBL6333854 | 0.79 | HCRTR2 (0.71) | HCRTR2HCRTR1ALDH1A1ABCB1KDM4E | |
| SCHEMBL6333557 | 0.78 | HCRTR2 (1.00) | HCRTR2HCRTR1ALDH1A1KDM4ETSHR | |
| SCHEMBL30417508 | 0.76 | HCRTR2 (1.00) | HCRTR2HCRTR1ALDH1A1KDM4ETSHR | |
| SCHEMBL12978652 | 0.76 | HCRTR2 (1.00) | HCRTR2HCRTR1ALDH1A1KDM4ETSHR | |
| SCHEMBL6326464 | 0.76 | HCRTR2 (1.00) | HCRTR2HCRTR1ALDH1A1KDM4ETSHR | |
| SCHEMBL264626 | 0.76 | HCRTR2 (1.00) | HCRTR2HCRTR1ALDH1A1KDM4ETSHR | |
| SCHEMBL6331702 | 0.75 | HCRTR2 (0.71) | HCRTR2HCRTR1ALDH1A1KDM4ETSHR | |
| Hydrochloric Acid SCHEMBL15544842 | 0.75 | HCRTR2 (0.98) | HCRTR2HCRTR1ALDH1A1KDM4ETSHR | |
| SCHEMBL6334190 | 0.75 | HCRTR2 (0.70) | HCRTR2HCRTR1ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1288202-A1 | N-ACYLTETRAHYDROISOQUINOLINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2003-03-05 | — | — | EP | disclosed |