SCHEMBL6983314

SCHEMBL6983314

N[C@@H](CC(=O)O)c1cccc(Cl)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
MEN1 O00255 2/20 0.51
ANPEP P15144 1/20 0.46
ENPEP Q07075 1/20 0.46
ACP3 P15309 1/20 0.46
CYP2D6 P10635 2/20 0.45
CYP2C9 P11712 2/20 0.45
CYP2C19 P33261 2/20 0.45
CTSA P10619 1/20 0.45
FFAR1 O14842 1/20 0.45
PNP P00491 2/20 0.44
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44
CACNA1G O43497 1/20 0.44
CACNA2D1 P54289 1/20 0.44
CACNA1B Q00975 1/20 0.44
CACNB1 Q02641 1/20 0.44
CACNA1C Q13936 1/20 0.44
GABBR2 O75899 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30861879 1.00 KMT2A (0.55) KMT2ASMN1; SMN2MEN1ANPEPENPEP
SCHEMBL1198080 1.00 KMT2A (0.55) KMT2ASMN1; SMN2MEN1ANPEPENPEP
SCHEMBL5720954 1.00 KMT2A (0.55) KMT2ASMN1; SMN2MEN1ANPEPENPEP
Hydrochloric Acid SCHEMBL7594743 0.98 KMT2A (0.54) KMT2ASMN1; SMN2MEN1ANPEPENPEP
Hydrochloric Acid SCHEMBL6773954 0.98 KMT2A (0.54) KMT2ASMN1; SMN2MEN1ANPEPENPEP
Hydrochloric Acid SCHEMBL7589162 0.98 KMT2A (0.54) KMT2ASMN1; SMN2MEN1ANPEPENPEP
SCHEMBL20545260 0.91 CTSA (0.56) KMT2ASMN1; SMN2MEN1ANPEPENPEP
SCHEMBL20545257 0.91 CTSA (0.56) KMT2ASMN1; SMN2MEN1ANPEPENPEP
SCHEMBL20546108 0.88 KMT2A (0.54) KMT2ASMN1; SMN2MEN1CTSAFFAR1
SCHEMBL30644987 0.88 KMT2A (0.54) KMT2ASMN1; SMN2MEN1CTSAFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1050530-B1 1-Aza-2-alkyl-6-aryl-cycloalkanes usefull as memory enhancers SERVIER LAB (FR) 2003-10-22 EP disclosed
EP-1050530-A1 1-Aza-2-alkyl-6-aryl-cycloalkanes usefull as memory enhancers ADIR ET COMPAGNIE (FR) 2000-11-08 EP disclosed