SCHEMBL6983427

SCHEMBL6983427

CC(F)C(F)[C](F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15403759 0.79 TSHR (0.32)
SCHEMBL17451074 0.77
SCHEMBL22359058 0.72
SCHEMBL5943396 0.72
SCHEMBL36690 0.70
SCHEMBL21243282 0.67
SCHEMBL4922154 0.67
SCHEMBL1470233 0.67
SCHEMBL979935 0.65
SCHEMBL7618534 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2684870-A1 METHOD FOR PREPARING THIOCARBOXYLIC ACID S-(FLUOROALKYL) ESTER Sumitomo Chemical Company Limited (JP) 2014-01-15 EP disclosed
CN-103347855-A Method for preparing thiocarboxylic acid s-(fluoroalkyl) ester SUMITOMO CHEMICAL CO 2013-10-09 CN disclosed
EP-0759755-B1 Thiadiazolylalkoxyphenyl derivatives, their preparation and their use anti-picornaviral agents SANOFI SYNTHELABO (FR) 2003-08-13 EP disclosed
CN-1095664-C Thiadiazoles and their use as antipicornaviral agent SANNOFFE SYNTHELAB S A (FR) 2002-12-11 CN disclosed
US-5846986-A Therapeutic phenoxyalkylazoles and phenoxyalkylazines SANOFI (FR) 1998-12-08 US disclosed
US-5821257-A Thiadiazoles and their uses as antipicornaviral agents SANOFI (FR) 1998-10-13 US disclosed
US-5763461-A ANTIPICORNAVIRAL AGENTS SANOFI (FR) 1998-06-09 US disclosed
US-5750527-A VIRICIDES SANOFI (FR) 1998-05-12 US disclosed
US-5721261-A TREATING PICORNAVIRUS INFECTIONS SANOFI PHARMACEUTICALS, INC. (US) 1998-02-24 US disclosed
US-5665763-A ANTIPICORNAVIRAL AGENTS SANOFI, S.A. (FR) 1997-09-09 US disclosed
US-5552420-A TREATING PICORNAVIRAL INFECTIONS STERLING WINTHROP INC. (US) 1996-09-03 US disclosed
US-5523312-A ADMINISTERING TO MAMMALS STERLING WINTHROP INC. (US) 1996-06-04 US disclosed
US-5514692-A VIRICIDES STERLING WINTHROP INC. (US) 1996-05-07 US disclosed
US-5514679-A TREATMENT OF PICORNAVIRUS INFECTIONS STERLING WINTHROP INC. (US) 1996-05-07 US disclosed
WO-1996009822-A1 ANTIPICORNAVIRAL AGENTS SANOFI WINTHROP, INC. (US) 1996-04-04 WO disclosed
WO-1995031438-A1 THERAPEUTIC PHENOXYALKYLHETEROCYCLES SANOFI WINTHROP, INC. (US) 1995-11-23 WO disclosed
WO-1995031439-A1 THERAPEUTIC PHENOXYALKYLPYRIDAZINES AND INTERMEDIATES THEREFOR SANOFI WINTHROP, INC. (US) 1995-11-23 WO disclosed
WO-1995031452-A1 THERAPEUTIC PHENOXYALKYLAZOLES AND PHENOXYALKYLAZINES SANOFI WINTHROP, INC. (US) 1995-11-23 WO disclosed
WO-1995031198-A1 THIADIAZOLES AND THEIR USE AS ANTIPICORNAVIRAL AGENTS SANOFI WINTHROP, INC. (US) 1995-11-23 WO disclosed
US-5453433-A Viricides; antiseptics to decontaminate polio, rhino and coxsackie viruses STERLING WINTHROP INC. (US) 1995-09-26 US disclosed