Bisphenol A

Bisphenol A

SCHEMBL6984040

CC(=CCCCO)C(=O)O.CC(=CCCCO)C(=O)O.CC(C)(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.46
ESR2 Q92731 6/20 0.46
CYP3A4 P08684 3/20 0.46
ESRRG P62508 3/20 0.46
AR P10275 1/20 0.46
HPGD P15428 1/20 0.46
TSHR P16473 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A4 P31645 1/20 0.46
HTR6 P50406 1/20 0.46
SLC6A3 Q01959 1/20 0.46
HSD17B10 Q99714 1/20 0.46
ALDH1A1 P00352 5/20 0.45
KDM4E B2RXH2 3/20 0.37
LMNA P02545 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
POLB P06746 1/20 0.37
SHBG P04278 1/20 0.37
TBXAS1 P24557 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bisphenol A SCHEMBL7457195 0.78 ESR1 (0.59) ESR1ESR2CYP3A4ESRRGAR
SCHEMBL149851 0.78 EP300 (0.39) TBXAS1BACE1PPARG
SCHEMBL16666 0.78 EP300 (0.39) TBXAS1BACE1PPARG
SCHEMBL27199826 0.77 KDM4E (0.54) ALDH1A1KDM4ELMNAMEN1KMT2A
Bisphenol A SCHEMBL29388682 0.76 ESR1 (0.52) ESR1ESR2CYP3A4ESRRGAR
Bisphenol A SCHEMBL9233341 0.75 ESR1 (0.43) ESR1ESR2CYP3A4ESRRGAR
SCHEMBL3190683 0.74 ESR1 (0.51) ESR1ESR2CYP3A4ESRRGAR
Bisphenol A SCHEMBL29483356 0.74 HPGD (0.43) ESR1ESR2CYP3A4ESRRGAR
SCHEMBL6552207 0.74 CD81 (0.37) TBXAS1BACE1PPARG
SCHEMBL7713666 0.74 EP300 (0.41) TBXAS1BACE1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0751161-B1 Sulfur-containing urethane-based resin composition, optical element and lens comprising this resin MITSUI CHEMICALS INC (JP) 2003-01-02 EP disclosed
EP-0751161-A2 Sulfur-containing urethane-based resin composition, optical element and lens comprising this resin MITSUI TOATSU CHEMICALS, Inc. (JP) 1997-01-02 EP disclosed