SCHEMBL698413

SCHEMBL698413

CC(=O)c1c(C)cc(C)cc1C

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.46
HPGD P15428 3/20 0.44
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
CYP3A4 P08684 1/20 0.44
TAS1R3 Q7RTX0 3/20 0.42
TAS1R1 Q7RTX1 3/20 0.42
TAS1R2 Q8TE23 3/20 0.42
ALDH1A1 P00352 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
LMNA P02545 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
MCOLN3 Q8TDD5 1/20 0.41
TPMT P51580 1/20 0.40
FFAR4 Q5NUL3 1/20 0.40
MAPT P10636 2/20 0.39
MAPK1 P28482 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2648126 0.85 CYP3A4 (0.54) HPGDKMT2AMEN1CYP3A4SMN1; SMN2
SCHEMBL30597490 0.85 CYP3A4 (0.54) HPGDKMT2AMEN1CYP3A4SMN1; SMN2
SCHEMBL16976467 0.84 KDM4E (0.39) KDM4EHPGDKMT2AMEN1CYP3A4
SCHEMBL10101636 0.82 GAA (0.44) KDM4EHPGDKMT2AMEN1CYP3A4
SCHEMBL27964400 0.82 KDM4E (0.57) KDM4EHPGDCYP3A4ALDH1A1L3MBTL1
SCHEMBL2380154 0.81 CYP3A4 (0.61) HPGDKMT2AMEN1CYP3A4ALDH1A1
SCHEMBL16644713 0.80 CYP3A4 (0.55) KMT2ACYP3A4ALDH1A1LMNASMN1; SMN2
SCHEMBL2380706 0.80 SMN1; SMN2 (0.44) HPGDCYP3A4ALDH1A1LMNASMN1; SMN2
SCHEMBL6666412 0.80 HPGD (0.52) KDM4EHPGDKMT2AMEN1CYP3A4
SCHEMBL22109937 0.80 HPGD (0.47) KDM4EHPGDKMT2AMEN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 366 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116410077-A Preparation method of 2,4, 6-trimethyl benzoic acid 甘肃青宇新材料有限公司 2023-07-11 CN claimed
CN-108906124-B Application of rare earth metal tricyclocene complex as catalyst in catalysis of synthesis reaction of ketone and pinacol borane 苏州大学 2020-11-17 CN claimed
US-9174906-B2 Process for producing optically active secondary alcohol KANTO KAGAKU KABUSHIKI KAISHA (JP) 2015-11-03 US claimed
US-6833468-B2 Reacting an optically active imine with a compound that is a hemiacetal of a perfluoroalkylaldehyde or a hydrate of a perfluoroalkylaldehyde to obtain a condensate, hydrolyzing CENTRAL GLASS COMPANY, LIMITED (JP) 2004-12-21 US claimed
EP-0674233-B1 Recording sheets XEROX CORP (US) 2000-05-24 EP claimed
US-5928765-A Recording sheets XEROX CORPORATION (US) 1999-07-27 US claimed
EP-0674233-A2 Recording sheets XEROX CORPORATION (US) 1995-09-27 EP claimed
WO-1991010635-A1 PROCESS FOR PREPARING 2,4,6-TRIMETHYLACETOPHENONE HOECHST AKTIENGESELLSCHAFT (DE) 1991-07-25 WO claimed
EP-0043480-B1 PROCESS FOR FORMING METALLIC IMAGES Hitachi, Ltd. (JP) 1985-04-03 EP claimed
US-4347304-A PHOTOSENSITIZATION WITH DISILANES OR ORGANIC COMPOUNDS HAVING COUPLED GERMANIUM OR TIN MOLECULES; PHOTORESISTS; POSITIVES; PLATING HITACHI, LTD. (JP) 1982-08-31 US claimed
EP-3990503-B1 OLEFIN POLYMERIZATION CATALYSTS BEARING A THIAZOLE OR IMIDAZOLE DOW GLOBAL TECHNOLOGIES LLC (US) 2025-07-23 EP disclosed
US-12286502-B2 Olefin polymerization catalysts bearing a thiazole or imidazole DOW GLOBAL TECHNOLOGIES LLC (US) 2025-04-29 US disclosed
US-12042788-B2 Strongly Lewis acidic metal-organic frameworks for continuous flow catalysis THE UNIVERSITY OF CHICAGO (US) 2024-07-23 US disclosed
EP-3605093-B1 KIT AND METHOD FOR MEASURING MEASUREMENT TARGET SUBSTANCE IN BIOLOGICAL SAMPLE FUJIFILM CORP (JP) 2024-07-17 EP disclosed
CN-116964139-B Photoinitiator resin with dibenzoylmethane substructure 太阳化学有限公司 2024-07-12 CN disclosed
US-3987082-A PROSTAGLANDIN INTERMEDIATE MERCK & CO., INC. (US) 1976-10-19 US disclosed
US-3975373-A CYCLOPENTANONE HELVETICOSIDE JOHANN A. WULFING FABRIK PHARMAZEUTISCHER PRAPARATE (DT) 1976-08-17 US disclosed
US-3971825-A (5,6) (10,11) BIS-METHYLENE, BRONCHODILATORS SANKYO COMPANY LIMITED (JA) 1976-07-27 US disclosed
US-3951946-A Cardioglycoside derivatives of the strophanthidin type, a process for their manufacture and medicinal preparations containing these compounds JOHANN A. WULFING FABRIK PHARMAZEUTISCHER PRAPARATE (DT) 1976-04-20 US disclosed
US-3950359-A PROSTAGLANDINS AND METHODS OF MAKING SAME MERCK & CO., INC. (US) 1976-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12042788-B2 Strongly Lewis acidic metal-organic frameworks for continuous flow catalysis CD69, TECR, MCM4 KDM4E 1059/4885HPGD 945/4885KMT2A 1213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.