Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986843 | 0.80 | KMT2A (0.50) | CYP1A2CYP3A4CYP2C9CYP2C19HPGD | |
| SCHEMBL8300238 | 0.77 | KMT2A (0.55) | CYP1A2CYP3A4CYP2C9CYP2C19HPGD | |
| SCHEMBL6988454 | 0.77 | CYP1A2 (0.46) | CYP1A2CYP3A4CYP2C9CYP2C19HPGD | |
| SCHEMBL1168619 | 0.76 | PSEN1 (0.53) | CYP1A2CYP3A4CYP2C9CYP2C19HPGD | |
| SCHEMBL3699519 | 0.76 | KMT2A (0.57) | CYP1A2CYP3A4CYP2C9CYP2C19HPGD | |
| SCHEMBL6989391 | 0.75 | CYP1A2 (0.44) | CYP1A2CYP3A4CYP2C9CYP2C19HPGD | |
| SCHEMBL6987173 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2HTTTSHRLMNAMAPT | |
| SCHEMBL6982415 | 0.74 | KMT2A (0.66) | CYP1A2CYP3A4CYP2C9CYP2C19KMT2A | |
| SCHEMBL6987199 | 0.74 | KMT2A (0.45) | CYP1A2CYP3A4CYP2C9CYP2C19HPGD | |
| SCHEMBL6987211 | 0.74 | KMT2A (0.66) | CYP1A2CYP3A4CYP2C9CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341779-A2 | HETEROCYCLIC SULFONAMIDE INHIBITORS OF BETA AMYLOID PRODUCTION | Wyeth (US) | 2003-09-10 | — | — | EP | claimed |
| WO-2002057252-A2 | HETEROCYCLIC SULFONAMIDE INHIBITORS OF BETA AMYLOID PRODUCTION | WYETH (US) | 2002-07-25 | — | — | WO | claimed |