Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLI1 | P08151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1613612 | 0.79 | CYP2D6 (0.40) | — | |
| SCHEMBL3741722 | 0.79 | CYP2D6 (0.40) | — | |
| SCHEMBL19919907 | 0.72 | — | — | |
| SCHEMBL19919497 | 0.72 | — | — | |
| SCHEMBL1764799 | 0.72 | KMT2A (0.38) | — | |
| SCHEMBL29493878 | 0.70 | GLI1 (0.39) | GLI1 | |
| SCHEMBL2031312 | 0.69 | HRH3 (0.32) | — | |
| SCHEMBL2028983 | 0.69 | HRH3 (0.32) | — | |
| SCHEMBL2702821 | 0.65 | — | — | |
| SCHEMBL13045000 | 0.65 | GLI1 (0.32) | GLI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071471-A | Internal sulfonamide compounds and methods of use thereof | 正大天晴药业集团股份有限公司 | 2018-12-21 | — | — | CN | disclosed |
| EP-1322627-A1 | CYCLIC SULFONYL COMPOUNDS AS INHIBITORS OF METALLOPROTEASES | Bristol-Myers Squibb Pharma Company (US) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002028846-A1 | CYCLIC SULFONYL COMPOUNDS AS INHIBITORS OF METALLOPROTEASES | DUPONT PHARMACEUTICALS COMPANY (US) | 2002-04-11 | — | — | WO | disclosed |