SCHEMBL698482

SCHEMBL698482

C=CC(=O)OCCCC.O=C1CCCCCO1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.58
HPGD P15428 1/20 0.58
ALDH1A1 P00352 3/20 0.46
CYP3A4 P08684 1/20 0.46
CA1 P00915 1/20 0.42
CA9 Q16790 1/20 0.42
ATM Q13315 1/20 0.41
PRKCA P17252 5/20 0.41
THRB P10828 3/20 0.38
HCAR2 Q8TDS4 3/20 0.38
TP53 P04637 2/20 0.36
HIF1A Q16665 2/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL27771897 0.96 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4CA1
Acrylic Acid Ethyl Ester SCHEMBL27877556 0.96 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4CA1
Methacrylic Acid SCHEMBL252352 0.93 TSHR (0.50) TSHRHPGDALDH1A1CYP3A4CA1
SCHEMBL27756094 0.91 TSHR (0.48) TSHRHPGDALDH1A1CYP3A4CA1
SCHEMBL27832742 0.88 TSHR (0.47) TSHRHPGDALDH1A1CYP3A4CA1
Acrylic Acid Ethyl Ester SCHEMBL7637636 0.86 CA1 (0.47) TSHRHPGDALDH1A1CYP3A4CA1
Acrylic Acid Ethyl Ester SCHEMBL27769537 0.86 CA1 (0.47) TSHRHPGDALDH1A1CYP3A4CA1
SCHEMBL2561776 0.85 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4CA1
SCHEMBL28402764 0.85 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4CA1
SCHEMBL28096995 0.82 CA1 (0.40) TSHRHPGDALDH1A1CYP3A4CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11793911-B2 Stent made of a bio-degradable magnesium alloy with a magnesium fluoride coating and an organic coating MEKO LASERSTRAHL-MATERIALBEARBEITUNGEN E.K. (DE) 2023-10-24 US claimed
US-11167065-B2 Shellac and paclitaxel coated catheter balloons EUROCOR TECH GMBH (DE) 2021-11-09 US claimed
US-20190275211-A1 SHELLAC AND PACLITAXEL COATED CATHETER BALLOONS EUROCOR TECH GMBH (DE) 2019-09-12 US claimed
EP-2384705-B1 Compound barb medical device COVIDIEN LP (US) 2017-05-03 EP claimed
EP-2249804-B1 IMPLANTABLE PRODUCTS COMPRISING NANOPARTICLES MAGFORCE AG (DE) 2016-12-14 EP claimed
EP-2421572-B1 SHELLAC AND PACLITAXEL COATED CATHETER BALLOONS BIOSENSORS EUROP S A (CH) 2016-08-31 EP claimed
EP-2114481-B1 BIODEGRADABLE VASCULAR SUPPORT HEMOTEQ AG (DE) 2015-09-30 EP claimed
EP-2380599-B1 Biactive substance in a barbed suture COVIDIEN LP (US) 2015-09-16 EP claimed
US-9034011-B2 Anchoring device COVIDIEN LP (US) 2015-05-19 US claimed
EP-2368501-B1 Knotted suture end effector COVIDIEN LP (US) 2015-04-22 EP claimed
US-20100268272-A1 ANCHORING DEVICE COVIDIEN LP 2010-10-21 US claimed
US-20100228270-A1 Deployment System for Surgical Suture COVIDIEN LP 2010-09-09 US claimed
US-20100211098-A1 Compound Barb Medical Device and Method COVIDIEN LP 2010-08-19 US claimed
US-20100204730-A1 Knotted Suture End Effector COVIDIEN LP 2010-08-12 US claimed
US-20100204729-A1 Tapered Looped Suture COVIDIEN LP 2010-08-12 US claimed
US-20100198257-A1 Bioactive Substance in a Barbed Suture COVIDIEN LP 2010-08-05 US claimed
US-20100145266-A1 METHOD FOR LOADING STRUCTURED SURFACES EUROCOR GMBH (DE) 2010-06-10 US claimed
US-20100076544-A1 BIODEGRADABLE VASCULAR SUPPORT HEMOTEQ AG (DE) 2010-03-25 US claimed
EP-1501566-B1 MEDICAL PRODUCTS COMPRISING A HAEMOCOMPATIBLE COATING, PRODUCTION AND USE THEREOF HEMOTEQ AG (DE) 2008-08-13 EP claimed
CN-1665554-A Compounds and method for coating surfaces in a haemocompatible manner HEMOTEQ GMBH (DE) 2005-09-07 CN claimed