Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TLR3 | O15455 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2472077 | 1.00 | AKR1B1 (0.37) | AKR1B1HTTLMNASMN1; SMN2MAPT | |
| SCHEMBL5275472 | 1.00 | AKR1B1 (0.37) | AKR1B1HTTLMNASMN1; SMN2MAPT | |
| SCHEMBL4863606 | 1.00 | AKR1B1 (0.37) | AKR1B1HTTLMNASMN1; SMN2MAPT | |
| SCHEMBL2475336 | 1.00 | AKR1B1 (0.37) | AKR1B1HTTLMNASMN1; SMN2MAPT | |
| SCHEMBL6985781 | 1.00 | AKR1B1 (0.37) | AKR1B1HTTLMNASMN1; SMN2MAPT | |
| SCHEMBL2471965 | 1.00 | AKR1B1 (0.37) | AKR1B1HTTLMNASMN1; SMN2MAPT | |
| SCHEMBL2473015 | 1.00 | AKR1B1 (0.37) | AKR1B1HTTLMNASMN1; SMN2MAPT | |
| SCHEMBL7684277 | 1.00 | AKR1B1 (0.37) | AKR1B1HTTLMNASMN1; SMN2MAPT | |
| SCHEMBL4869775 | 0.87 | AKR1B1 (0.37) | AKR1B1HTTLMNASMN1; SMN2MAPT | |
| SCHEMBL4869825 | 0.87 | AKR1B1 (0.37) | AKR1B1HTTLMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1229371-C | Benzopyran guanidine derivatives, process for preparing the same, and pharmaceutical composition thereof | KOREA RES INST CHEM TECH (KR) | 2005-11-30 | — | — | CN | disclosed |
| EP-1228058-B1 | BENZOPYRANYL GUANIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DONGBU HANNONG CHEMICAL CO LTD (KR) | 2003-12-10 | — | — | EP | disclosed |
| CN-1382134-A | Benzopyranyl guanidine derivtives, process for preparation thereof and pharmaceutical compositions containing them | KOREA RES INST CHEM TECH (KR) | 2002-11-27 | — | — | CN | disclosed |
| US-6323238-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | DONGBU HANNONG CHEMICAL CO., LTD. (KR) | 2001-11-27 | — | — | US | disclosed |