Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 20/20 | 0.74 |
| ▸ | PPARG | P37231 | 14/20 | 0.74 |
| ▸ | PPARD | Q03181 | 9/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5123786 | 0.94 | PPARA (0.84) | PPARAPPARGPPARD | |
| SCHEMBL5208722 | 0.92 | PPARA (0.72) | PPARAPPARGPPARD | |
| SCHEMBL5210370 | 0.92 | PPARA (0.87) | PPARAPPARGPPARD | |
| SCHEMBL5210369 | 0.91 | PPARA (0.79) | PPARAPPARGPPARD | |
| SCHEMBL5207516 | 0.90 | PPARA (0.83) | PPARAPPARGPPARD | |
| SCHEMBL5117320 | 0.90 | PPARA (0.83) | PPARAPPARGPPARD | |
| SCHEMBL5209099 | 0.90 | PPARA (0.80) | PPARAPPARGPPARD | |
| SCHEMBL5209545 | 0.90 | PPARA (0.80) | PPARAPPARGPPARD | |
| SCHEMBL5204776 | 0.89 | PPARA (0.74) | PPARAPPARGPPARD | |
| SCHEMBL5205912 | 0.89 | PPARA (0.71) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313717-A1 | OXAZOLYL-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-05-28 | — | — | EP | claimed |
| WO-2002016332-A1 | OXAZOLYL-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-02-28 | — | — | WO | claimed |
| EP-1313717-A1 | OXAZOLYL-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002016332-A1 | OXAZOLYL-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-02-28 | — | — | WO | disclosed |