Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | KDM6B | O15054 | 1/20 | 0.57 |
| ▸ | KDM5C | P41229 | 1/20 | 0.57 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.57 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.57 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 3/20 | 0.54 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | PLAT | P00750 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL29137650 | 0.95 | TSHR (0.58) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL2490695 | 0.93 | PARP1 (0.61) | KDM4ETSHRPARP1LOXL2ALDH1A1 | |
| SCHEMBL29864637 | 0.93 | PARP1 (0.61) | KDM4ETSHRPARP1LOXL2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29016784 | 0.91 | PARP1 (0.59) | TSHRPARP1LOXL2ALDH1A1RAB9A | |
| Methylamine SCHEMBL28086442 | 0.91 | KDM4E (0.62) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL30262601 | 0.91 | KDM4E (0.66) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| Isophthalic Acid SCHEMBL5551894 | 0.91 | KDM4E (0.66) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL39797 | 0.91 | KDM4E (0.66) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| Hydrochloric Acid SCHEMBL5454358 | 0.89 | KDM4E (0.64) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| Water SCHEMBL28842117 | 0.89 | KDM4E (0.64) | KDM4EKDM6BKDM5CKDM4CKDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358160-A1 | AMINAL DIONES AS POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002062761-A1 | AMINAL DIONES AS POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2002-08-15 | — | — | WO | disclosed |