Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | CPN1 | P15169 | 2/20 | 0.49 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.49 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983317 | 1.00 | MEN1 (0.63) | MEN1KMT2AROCK2CPN1CPB2 | |
| SCHEMBL6976406 | 1.00 | MEN1 (0.63) | MEN1KMT2AROCK2CPN1CPB2 | |
| Hydrochloric Acid SCHEMBL7594745 | 0.98 | MEN1 (0.61) | MEN1KMT2AROCK2CPN1CPB2 | |
| Hydrochloric Acid SCHEMBL7589164 | 0.98 | MEN1 (0.61) | MEN1KMT2AROCK2CPN1CPB2 | |
| SCHEMBL6366834 | 0.86 | MEN1 (0.67) | MEN1KMT2ACPN1CPB2ACP3 | |
| SCHEMBL6366829 | 0.86 | MEN1 (0.67) | MEN1KMT2ACPN1CPB2ACP3 | |
| SCHEMBL6366838 | 0.86 | MEN1 (0.67) | MEN1KMT2ACPN1CPB2ACP3 | |
| SCHEMBL2109907 | 0.83 | MEN1 (0.63) | MEN1KMT2ACPN1CPB2ACP3 | |
| SCHEMBL3450850 | 0.83 | MEN1 (0.72) | MEN1KMT2ACPN1CPB2ACP3 | |
| SCHEMBL15552555 | 0.80 | MEN1 (0.60) | MEN1KMT2ACPN1CPB2ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1050530-B1 | 1-Aza-2-alkyl-6-aryl-cycloalkanes usefull as memory enhancers | SERVIER LAB (FR) | 2003-10-22 | — | — | EP | disclosed |
| EP-1050530-A1 | 1-Aza-2-alkyl-6-aryl-cycloalkanes usefull as memory enhancers | ADIR ET COMPAGNIE (FR) | 2000-11-08 | — | — | EP | disclosed |