Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | HRH2 | P25021 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | MC4R | P32245 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | CCKAR | P32238 | 2/20 | 0.50 |
| ▸ | CCKBR | P32239 | 2/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6708057 | 0.87 | KMT2A (0.69) | KMT2APABPC1MAPK1MEN1HRH2 | |
| SCHEMBL6708055 | 0.87 | KMT2A (0.69) | KMT2APABPC1MAPK1MEN1HRH2 | |
| SCHEMBL6983547 | 0.87 | KDM4E (0.63) | KMT2APABPC1MAPK1MEN1HRH2 | |
| SCHEMBL6986093 | 0.87 | MAPK1 (0.56) | KMT2AMAPK1MEN1HRH2HRH1 | |
| SCHEMBL27340724 | 0.85 | KMT2A (0.64) | KMT2APABPC1MAPK1HRH2HRH1 | |
| SCHEMBL13291363 | 0.85 | KMT2A (0.64) | KMT2APABPC1MAPK1HRH2HRH1 | |
| SCHEMBL5408063 | 0.85 | KMT2A (0.67) | KMT2APABPC1MAPK1HRH2HRH1 | |
| SCHEMBL4900321 | 0.85 | KMT2A (0.67) | KMT2APABPC1MAPK1HRH2HRH1 | |
| SCHEMBL6350465 | 0.84 | KMT2A (0.66) | KMT2APABPC1MAPK1HRH2HRH1 | |
| SCHEMBL15809950 | 0.83 | KMT2A (0.62) | KMT2APABPC1MAPK1HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6551999-B1 | For therapy and prophylaxis of angiogenesis associated with wound healing, inflammation, growth of tumor and the like; angiogenesis as seen in diabetic retinopathy, prematurity retinopathy, retinal venous occlusion, metastasis of tumors | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2003-04-22 | — | — | US | disclosed |
| EP-0771565-B1 | Angiogenesis inhibitor | SENJU PHARMA CO (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-6214800-B1 | ANGIOGENESIS INHIBITORS | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2001-04-10 | — | — | US | disclosed |
| US-6057290-A | ADMINISTERING A CYSTEINE PROTEASE INHIBITOR TO A PATIENT FOR INHIBITING ANGIOGENESIS | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| US-5935959-A | CYSTEINE PROTEASE INHIBITORS | SENJU PHARMACEUTICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0928786-A1 | Angiogenesis inhibitor | Senju Pharmaceutical Co., Ltd. (JP) | 1999-07-14 | — | — | EP | disclosed |
| EP-0927716-A1 | Angiogenesis inhibitor | Senju Pharmaceutical Co., Ltd. (JP) | 1999-07-07 | — | — | EP | disclosed |
| EP-0838460-A1 | PIPERAZINE DERIVATIVES AND USE OF THE SAME | Senju Pharmaceutical Co., Ltd. (JP) | 1998-04-29 | — | — | EP | disclosed |
| CN-1163145-A | Inhibiting agent for vascular formation | SENJI SEIYAKU K K (JP) | 1997-10-29 | — | — | CN | disclosed |
| EP-0771565-A2 | Angiogenesis inhibitor | Senju Pharmaceutical Co., Ltd. (JP) | 1997-05-07 | — | — | EP | disclosed |