Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.56 |
| ▸ | FNTA | P49354 | 8/20 | 0.53 |
| ▸ | FNTB | P49356 | 8/20 | 0.53 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6988442 | 0.79 | CYP11B1 (0.56) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL6711134 | 0.78 | POLB (0.50) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL6986083 | 0.77 | CYP11B1 (0.57) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL6754946 | 0.75 | POLB (0.44) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL7834672 | 0.73 | FNTA (0.66) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL5891899 | 0.73 | CYP11B1 (0.68) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL7083825 | 0.73 | CYP11B1 (0.76) | CYP11B1CYP11B2FNTAFNTB | |
| SCHEMBL2786255 | 0.73 | CYP11B1 (0.71) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL6986013 | 0.72 | CYP11B1 (0.53) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL1949482 | 0.72 | CYP11B1 (1.00) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1324999-A1 | NOVEL AMINOPHENYL PIPERAZINE OR AMINOPHENYL PIPERIDINE DERIVATIVES INHIBITING PRENYL TRANSFERASE PROTEINS AND METHODS FOR PREPARING SAME | PIERRE FABRE MEDICAMENT (FR) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002030927-A1 | NOVEL AMINOPHENYL PIPERAZINE OR AMINOPHENYL PIPERIDINE DERIVATIVES INHIBITING PRENYL TRANSFERASE PROTEINS AND METHODS FOR PREPARING SAME | PIERRE FABRE MEDICAMENT (FR) | 2002-04-18 | — | — | WO | disclosed |