Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 10/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6929325 | 0.75 | SMN1; SMN2 (0.53) | SMN1; SMN2CYP2C19NPC1RAB9AFNTA | |
| SCHEMBL3599930 | 0.73 | SMN1; SMN2 (0.80) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL948076 | 0.72 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP2C19NPC1RAB9AFNTA | |
| SCHEMBL8549475 | 0.71 | SMN1; SMN2 (0.65) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL6997163 | 0.71 | SMN1; SMN2 (0.57) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL27694059 | 0.71 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL2712105 | 0.70 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL1259833 | 0.70 | SMN1; SMN2 (0.66) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL4760522 | 0.70 | SMN1; SMN2 (0.74) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL618472 | 0.70 | SMN1; SMN2 (0.74) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045846-B1 | IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD (KR) | 2003-05-02 | — | — | EP | disclosed |
| EP-1045846-A1 | IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LIMITED (KR) | 2000-10-25 | — | — | EP | disclosed |
| WO-1999028315-A1 | IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD. (KR) | 1999-06-10 | — | — | WO | disclosed |