Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NFKBIA | P25963 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7202401 | 0.83 | KMT2A (0.43) | KMT2AMEN1SMN1; SMN2TSHRHTT | |
| SCHEMBL5502707 | 0.83 | CA1 (0.45) | KMT2AMEN1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL6987172 | 0.79 | KMT2A (0.42) | KMT2AMEN1SMN1; SMN2TSHRHTT | |
| SCHEMBL6982397 | 0.76 | KMT2A (0.43) | KMT2AMEN1SMN1; SMN2TSHRHTT | |
| SCHEMBL1168809 | 0.74 | PSEN1 (0.41) | KMT2AMEN1SMN1; SMN2TSHRHTT | |
| SCHEMBL1168811 | 0.74 | PSEN1 (0.41) | KMT2AMEN1SMN1; SMN2TSHRHTT | |
| SCHEMBL6984609 | 0.74 | KMT2A (0.49) | KMT2AMEN1SMN1; SMN2TSHRHTT | |
| SCHEMBL6986868 | 0.72 | KMT2A (0.50) | KMT2AMEN1SMN1; SMN2TSHRHTT | |
| SCHEMBL6986543 | 0.72 | KMT2A (0.52) | KMT2AMEN1SMN1; SMN2TSHRHTT | |
| SCHEMBL6985763 | 0.70 | KMT2A (0.48) | KMT2AMEN1SMN1; SMN2TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341779-A2 | HETEROCYCLIC SULFONAMIDE INHIBITORS OF BETA AMYLOID PRODUCTION | Wyeth (US) | 2003-09-10 | — | — | EP | claimed |
| WO-2002057252-A2 | HETEROCYCLIC SULFONAMIDE INHIBITORS OF BETA AMYLOID PRODUCTION | WYETH (US) | 2002-07-25 | — | — | WO | claimed |