Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 20/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.65 |
| ▸ | HTR2A | P28223 | 2/20 | 0.63 |
| ▸ | DRD2 | P14416 | 1/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6343897 | 0.92 | CCR3 (0.81) | CCR3CYP2D6HTR2ADRD2SLC6A2 | |
| SCHEMBL6343902 | 0.92 | CCR3 (0.81) | CCR3CYP2D6HTR2ADRD2SLC6A2 | |
| SCHEMBL6982616 | 0.88 | CCR3 (0.70) | CCR3CYP2D6HTR2ADRD2SLC6A2 | |
| SCHEMBL6345312 | 0.86 | CCR3 (0.81) | CCR3CYP2D6HTR2ADRD2SLC6A2 | |
| SCHEMBL6351369 | 0.86 | CCR3 (0.81) | CCR3CYP2D6HTR2ADRD2SLC6A2 | |
| SCHEMBL6351373 | 0.86 | CCR3 (0.81) | CCR3CYP2D6HTR2ADRD2SLC6A2 | |
| SCHEMBL6345316 | 0.86 | CCR3 (0.81) | CCR3CYP2D6HTR2ADRD2SLC6A2 | |
| SCHEMBL6344104 | 0.83 | CCR3 (0.85) | CCR3CYP2D6HTR2ADRD2SLC6A2 | |
| SCHEMBL6344100 | 0.83 | CCR3 (0.85) | CCR3CYP2D6HTR2ADRD2SLC6A2 | |
| SCHEMBL18840884 | 0.83 | CCR3 (1.00) | CCR3CYP2D6HTR2ADRD2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1296978-A2 | N-UREIDOHETEROCYCLOAKLYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-04-02 | — | — | EP | disclosed |
| WO-2002002525-A2 | N-UREIDOHETEROCYCLOAKLYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-01-10 | — | — | WO | disclosed |