Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 9/20 | 0.62 |
| ▸ | AVPR2 | P30518 | 7/20 | 0.62 |
| ▸ | OXTR | P30559 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6993820 | 0.99 | AVPR1A (0.61) | AVPR1AAVPR2OXTR | |
| Conivaptan SCHEMBL4625101 | 0.91 | AVPR2 (0.75) | AVPR1AAVPR2OXTR | |
| Conivaptan SCHEMBL29406590 | 0.91 | AVPR2 (0.75) | AVPR1AAVPR2OXTR | |
| SCHEMBL6994333 | 0.91 | AVPR2 (0.61) | AVPR1AAVPR2OXTR | |
| Conivaptan SCHEMBL387232 | 0.90 | AVPR2 (0.74) | AVPR1AAVPR2OXTR | |
| Hydrochloric Acid SCHEMBL6992455 | 0.90 | AVPR2 (0.60) | AVPR1AAVPR2OXTR | |
| Hydrochloric Acid SCHEMBL6985748 | 0.90 | AVPR2 (0.60) | AVPR1AAVPR2OXTR | |
| SCHEMBL6987926 | 0.90 | AVPR2 (0.68) | AVPR1AAVPR2OXTR | |
| Hydrochloric Acid SCHEMBL6988764 | 0.89 | AVPR2 (0.67) | AVPR1AAVPR2OXTR | |
| Hydrochloric Acid SCHEMBL6986424 | 0.89 | AVPR2 (0.58) | AVPR1AAVPR2OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709386-B1 | FUSED BENZAZEPINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | YAMANOUCHI PHARMA CO LTD (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-1097920-A1 | Intermediate for condensed benzazepine derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2001-05-09 | — | — | EP | disclosed |
| EP-0709386-A1 | FUSED BENZAZEPINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-05-01 | — | — | EP | disclosed |