SCHEMBL698666

SCHEMBL698666

Ic1ccc(/C=C/c2cccc(I)c2)cc1

nearest known ligand 0.74

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
APP P05067 4/20 0.74
NFE2L2 Q16236 4/20 0.47
CYP19A1 P11511 3/20 0.47
RELA Q04206 3/20 0.43
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
LCK P06239 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL698667 1.00 APP (0.74) APPNFE2L2CYP19A1RELAMAOA
SCHEMBL20721903 0.91 APP (0.61) APPNFE2L2CYP19A1RELAMAOA
SCHEMBL20721905 0.91 APP (0.61) APPNFE2L2CYP19A1RELAMAOA
SCHEMBL698580 0.91 APP (0.72) APPNFE2L2CYP19A1RELAMAOA
SCHEMBL698579 0.91 APP (0.72) APPNFE2L2CYP19A1RELAMAOA
SCHEMBL699967 0.88 APP (0.70) APPNFE2L2CYP19A1RELAMAOA
SCHEMBL29446277 0.88 APP (0.70) APPNFE2L2CYP19A1RELAMAOA
SCHEMBL699966 0.88 APP (0.70) APPNFE2L2CYP19A1RELAMAOA
SCHEMBL15177970 0.85 APP (0.67) APPNFE2L2CYP19A1RELA
SCHEMBL2945509 0.85 APP (1.00) APPNFE2L2CYP19A1RELAMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8703388-B2 Optical data storage media GENERAL ELECTRIC COMPANY (US) 2014-04-22 US disclosed
US-8507153-B2 Compositions, optical data storage media and methods for using the optical data storage media GENERAL ELECTRIC COMPANY (US) 2013-08-13 US disclosed
EP-2423917-B1 Use of chemically bonded dyes in holographic data storage media GEN ELECTRIC (US) 2013-08-07 EP disclosed
US-8343608-B2 Use of appended dyes in optical data storage media GENERAL ELECTRIC COMPANY (US) 2013-01-01 US disclosed
EP-2290651-B1 Compositions, optical data storage media and methods for using the optical data storage media GEN ELECTRIC (US) 2012-10-10 EP disclosed
EP-2290408-B1 Compositions, optical data storage media and methods for using the optical data storage media GEN ELECTRIC (US) 2012-08-15 EP disclosed
US-20120163145-A1 OPTICAL DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY (US) 2012-06-28 US disclosed
CN-102399456-A Use of appended dyes in optical data storage media GEN ELECTRIC 2012-04-04 CN disclosed
US-20120052232-A1 USE OF APPENDED DYES IN OPTICAL DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY (US) 2012-03-01 US disclosed
EP-2423917-A2 Use of chemically bonded dyes in holographic data storage media General Electric Company (US) 2012-02-29 EP disclosed
US-8124299-B2 Methods for using optical data storage media GENERAL ELECTRIC COMPANY (US) 2012-02-28 US disclosed
CN-102005220-A Compositions, optical data storage media and methods for using the optical data storage media GEN ELECTRIC 2011-04-06 CN disclosed
CN-102005222-A Compositions, optical data storage media and methods for using the optical data storage media GEN ELECTRIC 2011-04-06 CN disclosed
US-20110053054-A1 COMPOSITIONS, OPTICAL DATA STORAGE MEDIA AND METHODS FOR USING THE OPTICAL DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY (US) 2011-03-03 US disclosed
US-20110053055-A1 COMPOSITIONS, OPTICAL DATA STORAGE MEDIA AND METHODS FOR USING THE OPTICAL DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY (US) 2011-03-03 US disclosed
EP-2290408-A1 Compositions, optical data storage media and methods for using the optical data storage media General Electric Company (US) 2011-03-02 EP disclosed
EP-2290651-A1 Compositions, optical data storage media and methods for using the optical data storage media General Electric Company (US) 2011-03-02 EP disclosed
US-20100302927-A1 OPTICAL DATA STORAGE MEDIUM AND METHODS FOR USING THE SAME GENERAL ELECTRIC COMPANY (US) 2010-12-02 US disclosed