Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 16/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 16/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 14/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 14/20 | 0.55 |
| ▸ | F10 | P00742 | 16/20 | 0.48 |
| ▸ | F9 | P00740 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989752 | 0.93 | F10 (0.57) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL6989110 | 0.87 | PRSS1 (0.55) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL6985454 | 0.87 | F2 (0.54) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7066176 | 0.86 | PRSS1 (0.57) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL6986798 | 0.85 | F2 (0.59) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL6992346 | 0.84 | F2 (0.56) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL6990777 | 0.83 | F2 (0.54) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL6982174 | 0.83 | PRSS1 (0.56) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL6988286 | 0.82 | F2 (0.55) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL6988335 | 0.82 | F2 (0.57) | F2PRSS1PRSS2PRSS3F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301506-A1 | CYCLIC AMINO ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002006269-A1 | CYCLIC AMINO ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-01-24 | — | — | WO | disclosed |