Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.71 |
| ▸ | PPARA | Q07869 | 18/20 | 0.71 |
| ▸ | PPARD | Q03181 | 4/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6792621 | 0.88 | PPARG (0.70) | PPARGPPARAPPARD | |
| SCHEMBL7081636 | 0.81 | PPARG (0.78) | PPARGPPARAPPARD | |
| SCHEMBL7079320 | 0.81 | PPARG (0.95) | PPARGPPARAPPARD | |
| SCHEMBL6797752 | 0.79 | PPARG (0.79) | PPARGPPARAPPARD | |
| SCHEMBL7085033 | 0.79 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL7083301 | 0.79 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL7077858 | 0.79 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL7081789 | 0.78 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL7082314 | 0.77 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL7244058 | 0.77 | PPARG (0.84) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347755-A2 | BENZOPYRANCARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETES AND LIPID DISORDERS | Merck & Co., Inc. (US) | 2003-10-01 | — | — | EP | claimed |
| WO-2002060434-A2 | BENZOPYRANCARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETES AND LIPID DISORDERS | MERCK & CO., INC. (US) | 2002-08-08 | — | — | WO | claimed |
| EP-1347755-A2 | BENZOPYRANCARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETES AND LIPID DISORDERS | Merck & Co., Inc. (US) | 2003-10-01 | — | — | EP | disclosed |
| WO-2002060434-A2 | BENZOPYRANCARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETES AND LIPID DISORDERS | MERCK & CO., INC. (US) | 2002-08-08 | — | — | WO | disclosed |