⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1042514 | 0.70 | — | — | |
| SCHEMBL4752878 | 0.70 | — | — | |
| SCHEMBL19957013 | 0.67 | — | — | |
| SCHEMBL24197698 | 0.65 | JAK2 (0.38) | — | |
| SCHEMBL11929996 | 0.65 | GSK3B (0.35) | — | |
| SCHEMBL578880 | 0.65 | — | — | |
| SCHEMBL25472564 | 0.65 | ADORA2A (0.32) | — | |
| SCHEMBL7175206 | 0.65 | — | — | |
| SCHEMBL2491558 | 0.65 | — | — | |
| SCHEMBL4031291 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5221845-A | — | — | None | — | — | JP | disclosed |
| CN-116490186-A | Compounds for targeted degradation of RET | C4医药公司 | 2023-07-25 | — | — | CN | disclosed |
| US-9510593-B2 | S-benzylthiouracil compounds and methods of enhancing plant root growth | VALENT BIOSCIENCES CORPORATION (US) | 2016-12-06 | — | — | US | disclosed |
| US-9510593-B2 | S-benzylthiouracil compounds and methods of enhancing plant root growth | VALENT BIOSCIENCES CORPORATION (US) | 2016-12-06 | — | — | US | disclosed |
| US-20150201620-A1 | S-BENZYLTHIOURACIL COMPOUNDS AND METHODS OF ENHANCING PLANT ROOT GROWTH | VALENT BIOSCIENCES LLC | 2015-07-23 | — | — | US | disclosed |
| US-20150201620-A1 | S-BENZYLTHIOURACIL COMPOUNDS AND METHODS OF ENHANCING PLANT ROOT GROWTH | VALENT BIOSCIENCES LLC | 2015-07-23 | — | — | US | disclosed |
| WO-2015108938-A1 | S-BENZYLTHIOURACIL COMPOUNDS AND METHODS OF ENHANCING PLANT ROOT GROWTH | VALENT BIOSCIENCES CORPORATION (US) | 2015-07-23 | — | — | WO | disclosed |
| EP-0588858-B1 | IMIDAZO 2,1-b] 3]BENZAZEPINE DERIVATIVES, COMPOSITIONS AND METHOD OF USE | JANSSEN PHARMACEUTICA NV (BE) | 2003-09-17 | — | — | EP | disclosed |
| US-5468743-A | Imidazo[2,1-b]benzazepine derivatives, compositions and method of use | JANSSEN PHARMACEUTICA N.V. (BE) | 1995-11-21 | — | — | US | disclosed |
| EP-0588858-A1 | IMIDAZO 2,1-b] 3]BENZAZEPINE DERIVATIVES, COMPOSITIONS AND METHOD OF USE | JANSSEN PHARMACEUTICA N.V. (BE) | 1994-03-30 | — | — | EP | disclosed |
| JP-H05221845-A | TYROSINASE INHIBITOR AND DERMATIC EXTERNAL PREPARATION USING THE SAME | HISAMITSU PHARMACEUT CO INC | 1993-08-31 | — | — | JP | disclosed |
| WO-1992022551-A1 | IMIDAZO[2,1-b][3]BENZAZEPINE DERIVATIVES, COMPOSITIONS AND METHOD OF USE | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-12-23 | — | — | WO | disclosed |
| EP-0518435-A1 | Imidazo[2,1-b][3]benzazepine derivatives, compositions and method of use | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-12-16 | — | — | EP | disclosed |