Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 19/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 17/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 17/20 | 0.53 |
| ▸ | F2 | P00734 | 16/20 | 0.53 |
| ▸ | F9 | P00740 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987778 | 0.93 | F2 (0.52) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7059561 | 0.87 | F10 (0.58) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL6985947 | 0.83 | F10 (0.55) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL6987059 | 0.82 | F10 (0.60) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL6990509 | 0.81 | F10 (0.54) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL6986473 | 0.80 | F10 (0.58) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL6988504 | 0.80 | F10 (0.56) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7065482 | 0.80 | PRSS1 (0.54) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7091410 | 0.80 | F10 (0.55) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL6989752 | 0.80 | F10 (0.57) | F10PRSS1PRSS2PRSS3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301506-A1 | CYCLIC AMINO ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002006269-A1 | CYCLIC AMINO ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-01-24 | — | — | WO | disclosed |