SCHEMBL6987739

SCHEMBL6987739

Cn1c(CCc2ccc(C(=N)N)cc2)nc2cc(N(CCN3C=CC=CC=C3)S(=O)(=O)c3ccccc3)ccc21

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2 P00734 20/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7670676 0.89 F2 (0.69) F2
SCHEMBL6974717 0.88 F2 (0.62) F2
SCHEMBL6985103 0.87 F2 (0.66) F2
SCHEMBL6983757 0.87 F2 (0.63) F2
SCHEMBL6986249 0.87 F2 (0.61) F2
Hydrochloric Acid SCHEMBL6986105 0.87 F2 (0.62) F2
SCHEMBL6635670 0.86 F2 (0.74) F2
SCHEMBL6979801 0.86 F2 (0.62) F2
SCHEMBL7668884 0.85 F2 (0.59) F2
SCHEMBL7664576 0.85 F2 (0.61) F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1220844-B1 ARYL SULFONAMIDE-SUBSTITUTED BENZIMIDAZOL DERIVATIVES THEREOF AS TRYPTASE INHIBITORS BOEHRINGER INGELHEIM PHARMA (DE) 2003-04-09 EP disclosed
US-6365584-B1 FOR PROPHYLAXIS AND THERAPY OF INFLAMMATORY AND/OR ALLERGIC DISEASES, LUNG FIBROSIS, FIBROSING ALVEOLITIS AND SCARRING, COLLAGENOSES SUCH AS LUPUS ERYTHEMATODES AND SCLERODERMIA AS WELL AS ARTERIOSCLEROSIS, PSORIASIS AND NEOPLASM BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-04-02 US disclosed