⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL630693 | 0.81 | — | — | |
| SCHEMBL5895389 | 0.74 | — | — | |
| SCHEMBL11005558 | 0.73 | MEN1 (0.32) | — | |
| SCHEMBL19049167 | 0.70 | — | — | |
| SCHEMBL11103519 | 0.69 | — | — | |
| SCHEMBL1267744 | 0.67 | — | — | |
| SCHEMBL21565702 | 0.65 | — | — | |
| SCHEMBL8201407 | 0.65 | — | — | |
| SCHEMBL2541407 | 0.65 | — | — | |
| Iodide SCHEMBL11383402 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230277698-A1 | SILICON-CONTAINING LIGAND COMPOUNDS | Technische Universität München (DE) | 2023-09-07 | — | — | US | disclosed |
| EP-4185336-A1 | SILICON-CONTAINING LIGAND COMPOUNDS | Technische Universität München (DE) | 2023-05-31 | — | — | EP | disclosed |
| WO-2022018264-A1 | SILICON-CONTAINING LIGAND COMPOUNDS | Technische Universität München (DE) | 2022-01-27 | — | — | WO | disclosed |
| EP-3317673-B1 | NEW DIAGNOSTIC TOOLS FOR CHARCOT-MARIE-TOOTH DISEASE | PHARNEXT (FR) | 2021-05-26 | — | — | EP | disclosed |
| US-20180209997-A1 | DIAGNOSTIC TOOLS FOR CHARCOT-MARIE-TOOTH DISEASE | PHARNEXT (FR) | 2018-07-26 | — | — | US | disclosed |
| US-9945876-B2 | Diagnostic tools for charcot-marie-tooth disease | PHARNEXT (FR) | 2018-04-17 | — | — | US | disclosed |
| US-9494605-B2 | Diagnostic tools for charcot-marie-tooth disease | PHARNEXT (FR) | 2016-11-15 | — | — | US | disclosed |
| US-20150301069-A1 | DIAGNOSTIC TOOLS FOR CHARCOT-MARIE-TOOTH DISEASE | PHARNEXT (FR) | 2015-10-22 | — | — | US | disclosed |
| EP-2502079-B1 | NEW DIAGNOSTIC TOOLS FOR CHARCOT-MARIE-TOOTH DISEASE | PHARNEXT (FR) | 2015-01-28 | — | — | EP | disclosed |
| US-20130217036-A1 | NEW DIAGNOSTIC TOOLS FOR CHARCOT-MARIE-TOOTH DISEASE | PHARNEXT (FR) | 2013-08-22 | — | — | US | disclosed |
| EP-1351956-A1 | SEMICARBAZIDES AND THEIR USES AS CYCLIN DEPENDENT KINASE INHIBITORS | Bristol-Myers Squibb Pharma Company (US) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002046182-A1 | SEMICARBAZIDES AND THEIR USES AS CYCLIN DEPENDENT KINASE INHIBITORS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-06-13 | — | — | WO | disclosed |