Sugi Predict

Sugi Predict / Compounds / SCHEMBL6987927

SCHEMBL6987927

SCHEMBL6987927

CCCCCCC(=O)N(C)Cc1cccc(-c2ccc(CC3SC(=O)NC3=O)cc2)c1.CCCCCCCC(=O)N(C)Cc1cccc(-c2ccc(CC3SC(=O)NC3=O)cc2)c1

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ FFAR1 O14842 5/20 0.51
▸ AOC3 Q16853 7/20 0.44
▸ FSHR P23945 7/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6183217 1.00 FFAR1 (0.51) FFAR1AOC3FSHR
SCHEMBL6183069 1.00 FFAR1 (0.51) FFAR1AOC3FSHR
SCHEMBL6182509 1.00 FFAR1 (0.51) FFAR1AOC3FSHR
SCHEMBL6184372 1.00 FFAR1 (0.51) FFAR1AOC3FSHR
SCHEMBL6183077 0.99 FFAR1 (0.52) FFAR1AOC3FSHR
SCHEMBL5762681 0.93 FFAR1 (0.53) FFAR1AOC3
SCHEMBL5763775 0.93 FFAR1 (0.53) FFAR1AOC3
SCHEMBL6182122 0.92 FFAR1 (0.48) FFAR1
SCHEMBL5390713 0.91 FFAR1 (0.52) FFAR1AOC3
SCHEMBL5397263 0.91 FFAR1 (0.52) FFAR1AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1309575-A1 BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS Galderma Research & Development (FR) 2003-05-14 — — EP claimed
WO-2002012210-A9 BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS GALDERMA RES & DEV (FR) 2002-04-18 — — WO claimed
WO-2002012210-A1 BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS GALDERMA RESEARCH & DEVELOPMENT (FR) 2002-02-14 — — WO claimed