Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.49 |
| ▸ | PPARG | P37231 | 10/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | MPC2 | O95563 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6183090 | 0.93 | FFAR1 (0.55) | FFAR1PPARGRARGRXRAAKT1 | |
| SCHEMBL6183812 | 0.91 | FFAR1 (0.52) | FFAR1PPARGPPARAMPC2CYP2C8 | |
| SCHEMBL6184880 | 0.81 | FFAR1 (0.50) | FFAR1PPARGRARGRXRAABHD6 | |
| SCHEMBL6184172 | 0.80 | FFAR1 (0.59) | FFAR1PPARGRARGRXRAMPC2 | |
| SCHEMBL5399098 | 0.80 | FFAR1 (0.59) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL6184136 | 0.79 | PPARG (0.64) | FFAR1PPARGRARGRXRAPPARA | |
| SCHEMBL6184614 | 0.79 | FFAR1 (0.52) | FFAR1PPARGPPARAMPC2CYP2C8 | |
| SCHEMBL5399580 | 0.78 | FFAR1 (0.61) | FFAR1PPARGRARGRXRAPPARA | |
| SCHEMBL6182568 | 0.78 | FFAR1 (0.54) | FFAR1PPARGPPARAMPC2CYP2C8 | |
| SCHEMBL6183713 | 0.78 | FFAR1 (0.53) | FFAR1PPARGPPARAMPC2CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309575-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | Galderma Research & Development (FR) | 2003-05-14 | — | — | EP | claimed |
| WO-2002012210-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2002-02-14 | — | — | WO | claimed |
| WO-2002012210-A9 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RES & DEV (FR) | 2002-04-18 | — | — | WO | disclosed |