Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL652052 | 1.00 | MAPT (0.51) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL652441 | 0.93 | MAPT (0.42) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL653416 | 0.93 | MAPT (0.42) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL12382988 | 0.89 | MAPT (0.53) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL651165 | 0.88 | MAPT (0.52) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL651164 | 0.88 | MAPT (0.52) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL652061 | 0.87 | MAPT (0.56) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL652062 | 0.87 | MAPT (0.56) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL651556 | 0.86 | MAPT (0.53) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL651555 | 0.86 | MAPT (0.53) | MAPTLMNANPSR1RECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423204-A1 | THIAZOLIDINONE DERIVATIVE | SBI Biotech Co., Ltd. (JP) | 2012-02-29 | — | — | EP | disclosed |