Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 18/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7250434 | 0.92 | FDFT1 (0.65) | FDFT1 | |
| SCHEMBL7247999 | 0.90 | FDFT1 (0.60) | FDFT1 | |
| SCHEMBL7250735 | 0.87 | FDFT1 (0.64) | FDFT1 | |
| SCHEMBL4117554 | 0.85 | FDFT1 (0.70) | FDFT1 | |
| SCHEMBL7255821 | 0.85 | FDFT1 (0.60) | FDFT1 | |
| SCHEMBL7249613 | 0.85 | FDFT1 (0.65) | FDFT1 | |
| SCHEMBL7255476 | 0.85 | FDFT1 (0.61) | FDFT1 | |
| SCHEMBL7250038 | 0.85 | FDFT1 (0.72) | FDFT1 | |
| SCHEMBL4927392 | 0.85 | FDFT1 (0.77) | FDFT1 | |
| SCHEMBL7250351 | 0.84 | FDFT1 (0.73) | FDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292585-A1 | BENZOXAZEPINONES AND THEIR USE AS SQUALENE SYNTHASE INHIBITORS | Takeda Chemical Industries, Ltd. (JP) | 2003-03-19 | — | — | EP | disclosed |
| WO-2001098282-A1 | BENZOXAZEPINONES AND THEIR USE AS SQUALENE SYNTHASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 2001-12-27 | — | — | WO | disclosed |