Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL557663 | 0.73 | KDM4E (0.41) | — | |
| SCHEMBL7360850 | 0.72 | PIM1 (0.33) | ATMPIM1 | |
| SCHEMBL2814958 | 0.60 | ATM (0.65) | ATM | |
| SCHEMBL6986571 | 0.60 | PIM1 (0.33) | ATMPIM1 | |
| SCHEMBL26951480 | 0.57 | CYP17A1 (0.40) | ATMPIM1 | |
| SCHEMBL3431562 | 0.57 | — | — | |
| SCHEMBL12951374 | 0.57 | ATM (0.46) | ATMPIM1 | |
| SCHEMBL10547 | 0.56 | — | — | |
| SCHEMBL13910998 | 0.56 | ATM (0.50) | ATM | |
| SCHEMBL2553484 | 0.55 | ATM (0.56) | ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337251-A1 | MONOCYCLIC OR BICYCLIC CARBOCYCLES AND HETEROCYCLES AS FACTOR XA INHIBITORS | Bristol-Myers Squibb Pharma Company (US) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002102380-A1 | MONOCYCLIC OR BICYCLIC CARBOCYCLES AND HETEROCYCLES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-12-27 | — | — | WO | disclosed |