Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 12/20 | 0.76 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.52 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6996005 | 0.87 | NPY5R (1.00) | NPY5RFLT3NTRK3NTRK2KMT2A | |
| SCHEMBL6996063 | 0.82 | NPY5R (0.87) | NPY5RFLT3NTRK3NTRK2KMT2A | |
| SCHEMBL6992797 | 0.82 | NPY5R (0.86) | NPY5RFLT3NTRK3NTRK2KMT2A | |
| SCHEMBL6996863 | 0.78 | NPY5R (1.00) | NPY5RFLT3NTRK3NTRK2KMT2A | |
| SCHEMBL7001040 | 0.77 | NPY5R (0.80) | NPY5RFLT3NTRK3NTRK2KMT2A | |
| SCHEMBL7000363 | 0.75 | NPY5R (1.00) | NPY5RCSNK2A2CSNK2A1 | |
| SCHEMBL6998167 | 0.74 | NPY5R (0.67) | NPY5RFLT3NTRK3NTRK2KMT2A | |
| SCHEMBL6999159 | 0.73 | NPY5R (0.65) | NPY5RFLT3NTRK3NTRK2KMT2A | |
| SCHEMBL6992731 | 0.72 | NPY5R (0.64) | NPY5RFLT3NTRK3NTRK2KMT2A | |
| SCHEMBL7093968 | 0.72 | NPY5R (0.66) | NPY5RFLT3NTRK3NTRK2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945438-B1 | PYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-05 | — | — | EP | claimed |
| EP-0945438-A1 | PYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | claimed |
| EP-0945438-B1 | PYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-6057335-A | Pyrazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0945438-A1 | PYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |