Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 8/20 | 0.69 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.61 |
| ▸ | AVPR2 | P30518 | 6/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991584 | 0.92 | AVPR1A (0.72) | AVPR1AAVPR1BAVPR2MEN1KMT2A | |
| SCHEMBL6994023 | 0.91 | AVPR1A (0.68) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL6991600 | 0.91 | AVPR1A (0.58) | AVPR1AAVPR1BAVPR2MEN1KMT2A | |
| SCHEMBL6993363 | 0.90 | AVPR1A (0.67) | AVPR1AAVPR1BAVPR2HSD11B1 | |
| SCHEMBL6988119 | 0.89 | AVPR1A (0.71) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL6988983 | 0.88 | AVPR1A (0.79) | AVPR1AAVPR1BAVPR2HSD11B1MEN1 | |
| SCHEMBL6992414 | 0.88 | AVPR1A (0.66) | AVPR1AAVPR1BAVPR2MEN1KMT2A | |
| SCHEMBL6989325 | 0.88 | AVPR1A (0.64) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL6991577 | 0.86 | AVPR1A (0.68) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL6991357 | 0.85 | AVPR1A (0.68) | AVPR1AAVPR1BAVPR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-B1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2003-10-01 | — | — | EP | claimed |
| US-5654297-A | CONGESTIVE HEART FAILURE, CARDIOVASCULAR DISORDERS | AMERICAN CYANAMID COMPANY (US) | 1997-08-05 | — | — | US | claimed |
| WO-1996022294-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | claimed |
| EP-0811008-B1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2003-10-01 | — | — | EP | disclosed |
| US-5654297-A | CONGESTIVE HEART FAILURE, CARDIOVASCULAR DISORDERS | AMERICAN CYANAMID COMPANY (US) | 1997-08-05 | — | — | US | disclosed |
| WO-1996022294-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |