Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 4/20 | 0.34 |
| ▸ | ABL1 | P00519 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.33 |
| ▸ | PTPN12 | Q05209 | 2/20 | 0.33 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL653891 | 0.90 | MAPT (0.41) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL653892 | 0.90 | MAPT (0.41) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL10176524 | 0.89 | MAPT (0.40) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL10176480 | 0.87 | MAPT (0.41) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL10176507 | 0.85 | MAPT (0.40) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL10176532 | 0.85 | PTPN7 (0.44) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL10176547 | 0.85 | MAPT (0.47) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL650770 | 0.83 | MAPT (0.41) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL699657 | 0.83 | MAPT (0.41) | MAPTLMNANPSR1RECQLTDP1 | |
| SCHEMBL10176528 | 0.83 | MAPT (0.42) | MAPTLMNANPSR1RECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423204-A1 | THIAZOLIDINONE DERIVATIVE | SBI Biotech Co., Ltd. (JP) | 2012-02-29 | — | — | EP | disclosed |